She has an interest in understanding the cellular and endocrine dynamics leading from energy intake to an increase in adipose tissue mass and adipose tissue inflammation. Using a mouse model of diet-induced obesity she has been investigating how high fat diet alters hematopoietic stem cell and myeloid precursors contributing to systemic obesity-induced metainflammation and metabolic disease.

Research
Dr. Singer’s research is related to the pathogenesis of obesity-induced inflammation and the progression from this chronic inflammatory state to insulin resistance and diabetes.