Throughout his career, he has worked in diagnostic histopathology with a special interest in Thoracic Pathology, but has always maintained close links with the clinical practice of thoracic medicine, especially thoracic oncology. He has maintained an active research interest in his own laboratory as well as through national and international collaboration. He enjoys his ongoing commitments to under- and postgraduate teaching.

He has had a career long interest in lung cancer for over 35 years and has research interests in pulmonary pre-neoplasia and carcinogenesis, in lung tumour diagnosis and classification and in the identification of predictors of therapy response.