José Brea - Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS) and Department of Pharmacology, Universidade de Santiago de Compostela

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论文共 241 篇作者统计合作学者相似作者

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N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives As Fluorescent Probes to Detect Microglia Activation Through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)

Francesca Intranuovo,Maria Majellaro, Francesco Mastropasqua,Pietro Delre,Francesca Serena Abatematteo,Giuseppe Felice Mangiatordi,Angela Stefanachi,Jose Brea,Maria Isabel Loza,Chiara Riganti,Alessia Ligresti,Poulami Kumar, Daniela Esposito,Luigia Cristino, Alessandro Nicois, Lucia Gonzalez,Maria Grazia Perrone,Nicola Antonio Colabufo,Eddy Sotelo,Carmen Abate,Marialessandra Contino

JOURNAL OF MEDICINAL CHEMISTRY (2024)

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Design, Synthesis, and Biological Evaluation of Tetrahydropyrimidine Analogue As GSK-3β/Aβ Aggregation Inhibitor and Anti-Alzheimer’s Agent

Sukanya,Aina Bellver-Sanchis,Bhanwar Singh Choudhary,Sunil Kumar,Belen Perez,Anton Leandro Martinez Rodriguez,Jose Brea,Christian Grinan-Ferre,Ruchi Malik

BIOORGANIC CHEMISTRY (2024)

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Polymeric Nanocapsules Loaded with Poly(i:C) and Resiquimod to Reprogram Tumor-Associated Macrophages for the Treatment of Solid Tumors

Clement Anfray, Carmen Fernandez Varela,Aldo Ummarino,Akihiro Maeda,Marina Sironi,Sara Gandoy,Jose Brea,Maria Isabel Loza,Sergio Leon,Alfonso Calvo,Juan Correa,Eduardo Fernandez-Megia,Maria Jose Alonso,Paola Allavena,Jose Crecente-Campo,Fernando Torres Andon

FRONTIERS IN IMMUNOLOGY（2024）

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Exploring Biginelli-based Scaffolds As A2B Adenosine Receptor Antagonists: Unveiling Novel Structure-Activity Relationship Trends, Lead Compounds, and Potent Colorectal Anticancer Agents

Ruben Prieto-Diaz,Hugo Fojo-Carballo,Maria Majellaro,Tana Tandaric,Jhonny Azuaje,Jose Brea,Maria I. Loza,Jorge Barbazan,Gloria Salort, Meera Chotalia, Ivan Rodriguez-Pampin,Ana Mallo-Abreu,M. Rita Paleo,Xerardo Garcia-Mera,Francisco Ciruela,Hugo Gutierrez-de-Teran,Eddy Sotelo

BIOMEDICINE & PHARMACOTHERAPY (2024)

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In Vitro Models for Neuropathic Pain Phenotypic Screening in Brain Therapeutics

A. L. Martinez,J. Brea, D. Lopez, N. Cosme, M. Barro, X. Monroy,J. Burgueno,M. Merlos,M. I. Loza

PHARMACOLOGICAL RESEARCH (2024)

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High-Throughput Nephelometry Methodology for Qualitative Determination of Aqueous Solubility of Chemical Libraries

Jose Brea,Maria J. Varela,Geert A. Daudey,Maria I. Loza

SLAS DISCOVERYno. 3 (2024)

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G Protein-Specific Mechanisms in the Serotonin 5-HT2A Receptor Regulate Psychosis-Related Effects and Memory Deficits

Elk Kossatz,Rebeca Diez-Alarcia,Supriya A. Gaitonde,Carla Ramon-Duaso,Tomasz Maciej Stepniewski,David Aranda-Garcia,Itziar Muneta-Arrate, Elodie Tepaz,Suwipa Saen-Oon,Robert Soliva,Aida Shahraki, David Moreira,Jose Brea,Maria Isabel Loza,Rafael de la Torre,Peter Kolb,Michel Bouvier,J. Javier Meana,Patricia Robledo,Jana Selent

NATURE COMMUNICATIONSno. 1 (2024)

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Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties

Caterina Pont,Anna Sampietro,F. Javier Perez-Areales, Nunzia Cristiano, Agusti Albalat,Belen Perez,Manuela Bartolini,Angela De Simone,Vincenza Andrisano,Marta Barenys,Elisabet Teixido,Raimon Sabate,M. Isabel Loza,Jose Brea,Diego Munoz-Torrero

PHARMACEUTICSno. 8 (2024)

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Effect of Bulky N-Dibenzofuranylmethyl Substitution on the 5-HT2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine

Breno A. Soares,Thirumal Yempala, Dario Martinez-Afani,Williams Acevedo-Fuentes,Jose Brea,Maria Isabel Loza,Marta Cimadevila,Bruce K. Cassels

ACS CHEMICAL NEUROSCIENCE（2024）

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2-Aryladenine Derivatives As a Potent Scaffold for Adenosine Receptor Antagonists: the 6-Morpholino Derivatives

Filipe Areias,Carla Correia,Ashly Rocha,Sofia Teixeira,Marian Castro,Jose Brea,Huabin Hu,Jens Carlsson,Maria I. Loza,M. Fernanda Proenca,M. Alice Carvalho

MOLECULESno. 11 (2024)

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