Jonathan H Clarke

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论文共 184 篇作者统计合作学者相似作者

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P-Tau Ser356 is Associated with Alzheimer’s Disease Pathology and is Lowered in Brain Slice Cultures Using the NUAK Inhibitor WZ4003

Lewis W. Taylor,Elizabeth M. Simzer, Claire Pimblett, Oscar T. T. Lacey-Solymar,Robert I. McGeachan,Soraya Meftah,Jamie L. Rose,Maxwell P. Spires-Jones,Kristján Holt,James H. Catterson,Henner Koch,Imran Liaquat,Jonathan H. Clarke,John Skidmore,Colin Smith,Sam A. Booker,Paul M. Brennan,Tara L. Spires-Jones,Claire S. Durrant

Acta Neuropathologicano. 1 (2024): 1-21

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F88. A PHENOME-WIDE ASSOCIATION STUDY OF POLYGENIC SCORES FOR SCHIZOPHRENIA IN 100,000 CHINESE ADULTS

Baihan Wang,Sam Morris, Hannah Fry,Andri Iona,Jonathan Clarke,Robin G Walters,Zhengming Chen, Iona Y Millwood

European Neuropsychopharmacology (2024): 252-253

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Tau phosphorylated at serine 356 is associated with Alzheimer’s disease pathology and can be lowered in mouse and human brain tissue using the NUAK inhibitor WZ4003

Lewis W. Taylor,Elizabeth M. Simzer, Claire Pimblett, Oscar T.T. Lacey-Solymar,Robert I. McGeachan,Soraya Meftah,Jamie L. Rose,Maxwell P. Spires-Jones,James H. Catterson,Henner Koch,Imran Liaquat,Jonathan H. Clarke,John Skidmore,Sam A. Booker,Paul M. Brennan,Tara L. Spires-Jones,Claire S. Durrant

Acta Neuropathologica（2023）

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The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors As in Vivo-Ready Tool Molecules

Timothy P. C. Rooney,Gregory G. Aldred,Helen K. Boffey,Henriette M. G. Willems,Simon Edwards,Stephen J. Chawner,Duncan E. Scott,Christopher Green,David Winpenny,John Skidmore,Jonathan H. Clarke,Stephen P. Andrews

JOURNAL OF MEDICINAL CHEMISTRY（2023）

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The rational design of ARUK2007145, a dual inhibitor of the and isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)

Gregory Aldred,Timothy Rooney,Henriette Willems,Helen Boffey,Christopher Green,David Winpenny,John Skidmore,Jonathan Clarke,Stephen Andrews

RSC MEDICINAL CHEMISTRYno. 10 (2023): 2035-2047

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Identification of ARUK2002821 As an Isoform-Selective PI5P4Kα Inhibitor

Henriette M. G. Willems,Simon Edwards,Helen K. Boffey,Stephen J. Chawner,Christopher Green,Tamara Romero,David Winpenny,John Skidmore,Jonathan H. Clarke,Stephen P. Andrews

RSC medicinal chemistryno. 5 (2023): 934-946

引用4浏览0WOS引用

Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode

Helen K. Boffey,Timothy P. C. Rooney,Henriette M. G. Willems,Simon Edwards,Christopher Green,Tina Howard,Derek Ogg,Tamara Romero,Duncan E. Scott,David Winpenny,James Duce,John Skidmore,Jonathan H. Clarke,Stephen P. Andrews

JOURNAL OF MEDICINAL CHEMISTRY（2022）

引用11浏览0WOS引用

Systematic Investigation of the Permeability of Androgen Receptor PROTACs

Duncan E. Scott,Timothy P. C. Rooney,Elliott D. Bayle,Tashfina Mirza,Henriette M. G. Willems,Jonathan H. Clarke,Stephen P. Andrews,John Skidmore

ACS medicinal chemistry letters（2020）

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Phosphatidylinositol 5-Phosphate 4-Kinase

Jonathan H. Clarke,Robin F. Irvine

Springer eBookspp.3940-3949, (2018)

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论文共 184 篇作者统计合作学者相似作者