My lab focuses on the development of new treatment paradigms for lung cancer using three primary tools: genetic, epigenetic, and transcriptomic analyses; functional genomics using CRISPR-Cas9; and, high-fidelity patient-derived models of lung cancer. In addition to my primary research focus, I direct the Perlmutter Cancer Center Preclinical Therapeutics Program, which acquires viable human tumor cells from the clinic for the development of cancer models and tests experimental cancer therapeutics in the preclinical setting.