Mitchell is author or co-author of over 325 peer-reviewed articles in scholarly journals. He has coordinated the development team for a high-resolution powder diffractometer at the Advanced Photon Source, and led the Argonne major initiative in materials design and discovery. He has also led a project in the DOE Center of Excellence in Synthesis and Processing entitled ​“Spin Polarized Transport in Complex Oxides.” He was awarded the DOE Early Career Award and the Presidential Early Career Award for Scientists and Engineers in 1999 and 2000, respectively. He received the University of Chicago Distinguished Performance Award for Argonne Scientists in 2006. He is a Fellow of the American Physical Society, and a member of the American Physical Society, American Crystallographic Society, Materials Research Society, and American Chemical Society and has served on the Chair Line of the APS Division of Materials Physics.