基本信息
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Bio
Joel S. Bader, a professor in the Department of Biomedical Engineering, is a leading innovator in genomics and biotechnology. His research explores the connection between genotype and phenotype, relating an organism’s genetic material to its observable characteristics.
Bader develops new computational methods to define how inborn genetic variants and acquired mutations lead to disease, primarily complex genetic disorders and cancer, with the goal of identifying new therapeutic targets. He also leads synthetic biology projects that design and build entire chromosomes and genomes to create new forms of life. He also leads an effort to create cells that rely on RNA (ribonucleic acid) rather than DNA for their genetic information. In related efforts, Bader’s lab develops technologies for biosafety and biosecurity, preventing escape of engineered life and identifying evidence of genetic engineering in DNA samples.
Bader develops new computational methods to define how inborn genetic variants and acquired mutations lead to disease, primarily complex genetic disorders and cancer, with the goal of identifying new therapeutic targets. He also leads synthetic biology projects that design and build entire chromosomes and genomes to create new forms of life. He also leads an effort to create cells that rely on RNA (ribonucleic acid) rather than DNA for their genetic information. In related efforts, Bader’s lab develops technologies for biosafety and biosecurity, preventing escape of engineered life and identifying evidence of genetic engineering in DNA samples.
Research Interests
Papers共 253 篇Author StatisticsCo-AuthorSimilar Experts
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Tess E Peterson,Virginia S Hahn,Ruin Moaddel, Min Zhu,Sabina A Haberlen,Frank J Palella,Michael Plankey,Joel S Bader,Joao Ac Lima,Robert E Gerszten,Jerome I Rotter,Stephen S Rich,Susan R Heckbert,Gregory D Kirk,Damani A Piggott,Luigi Ferrucci,Joseph B Margolick,Todd T Brown,Katherine C Wu,Wendy S Post
medRxiv : the preprint server for health sciences (2024)
Aaron Adler,Joel S. Bader, Brian Basnight,Benjamin W. Booth,Jitong Cai, Elizabeth Cho,Joseph H. Collins,Yuchen Ge, John Grothendieck,Kevin Keating, Tyler Marshall,Anton Persikov, Helen Scott,Roy Siegelmann,Mona Singh, Allison Taggart, Benjamin Toll,Kenneth H. Wan, Daniel Wyschogrod,Fusun Yaman,Eric M. Young,Susan E. Celniker,Nicholas Roehner
ACS SYNTHETIC BIOLOGYno. 4 (2024): 1105-1115
medRxiv : the preprint server for health sciences (2024)
PLOS COMPUTATIONAL BIOLOGYno. 6 (2024)
Circulation Genomic and precision medicineno. 5 (2024): e004494-e004494
BMC Bioinformaticsno. 1 (2023): 1-22
Weimin Zhang,Luciana Lazar-Stefanita,Hitoyoshi Yamashita,Michael J. Shen,Leslie A. Mitchell,Hikaru Kurasawa,Evgenii Lobzaev,Viola Fanfani,Max A. B. Haase,Xiaoji Sun,Qingwen Jiang,Gregory W. Goldberg,David M. Ichikawa,Stephanie L. Lauer, Laura H. Mcculloch,Nicole Easo,S. Jiaming Lin,Brendan R. Camellato,Yinan Zhu,Jitong Cai,Zhuwei Xu,Yu Zhao, Maya Sacasa,Marcus B. Noyes,Joel S. Bader,Samuel Deutsch,Giovanni Stracquadanio,Yasunori Aizawa,Junbiao Dai,Jef D. Boeke
MOLECULAR CELLno. 23 (2023)
Yea Ji Jeong,Hildur Knutsdottir,Fatemeh Shojaeian,Michael G. Lerner,Maria F. Wissler,Elodie Henriet,Tammy Ng,Shalini Datta,Bernat Navarro-Serer,Peter Chianchiano,Benedict Kinny-Koester,Jacquelyn W. Zimmerman,Genevieve Stein-O'Brien,Matthias M. Gaida,James R. Eshleman,Ming-Tseh Lin,Elana J. Fertig,Andrew J. Ewald,Joel S. Bader,Laura D. Wood
JOURNAL OF CLINICAL INVESTIGATIONno. 8 (2023)
Yue Shen,Feng Gao,Yun Wang,Yuerong Wang,Ju Zheng,Jianhui Gong,Jintao Zhang,Zhouqing Luo,Daniel Schindler, Yang Deng,Weichao Ding, Tao Lin,Reem Swidah,Hongcui Zhao,Shuangying Jiang,Cheng Zeng,Shihong Chen,Tai Chen, Yong Wang,Yisha Luo,Leslie Mitchell,Joel S. Bader,Guojie Zhang,Xia Shen,Jian Wang,Xian Fu,Junbiao Dai,Jef D. Boeke,Huanming Yang,Xun Xu,Yizhi Cai
Cell Genomicsno. 11 (2023): 100364
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Author Statistics
#Papers: 254
#Citation: 42835
H-Index: 68
G-Index: 198
Sociability: 8
Diversity: 3
Activity: 157
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