Jeremy D Osko - Roy and Diana Vagelos Laboratories, University of Pennsylvania

基本信息

Career Trajectory

Bio

I received my PhD from The University of Pennsylvania, where I worked for Dr. David Christianson on histone deacetylase enzymes and polyamine deacetylases. I am currently a postdoctoral researcher at Princeton University, working for Dr. Nieng Yan on ryanodine receptors.

Research Interests

Papers共 15 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders

Jeremy D. Osko,Nicholas J. Porter,Christophe Decroos,Matthew S. Lee,Paris R. Watson,Sarah E. Raible,Ian D. Krantz,Matthew A. Deardorff,David W. Christianson

Journal of structural biology（2021）

Cited5Views0WOSBibtex

Structural determinants of affinity and selectivity in the binding of inhibitors to histone deacetylase 6

Jeremy D. Osko,David W. Christianson

Bioorganic & Medicinal Chemistry Letters（2020）

Cited28Views0WOSBibtex

Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups

Nina Ressing,Melf Soennichsen,Jeremy D. Osko,Andrea Schoeler,Julian Schliehe-Diecks,Alexander Skerhut,Arndt Borkhardt,Julia Hauer,Matthias U. Kassack,David W. Christianson,Sanil Bhatia,Finn K. Hansen

Journal of medicinal chemistry（2020）

Cited24Views0WOSBibtex

Binding of Inhibitors to Active-Site Mutants of CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6

Jeremy D. Osko,David W. Christianson

Acta crystallographica Section F, Structural biology communications（2020）

Cited3Views0WOSBibtex

Structural Determinants of Affinity and Selectivity in the Binding of Inhibitors to Histone Deacetylase 6

Jeremy D. Osko,David W. Christianson

BIOORGANIC & MEDICINAL CHEMISTRY LETTERSno. 8 (2020)

Cited0Views0Bibtex

Design and Synthesis of Dihydroxamic Acids As HDAC6/8/10 Inhibitors

Michael Morgen,Raphael R. Steimbach,Magalie Geraldy,Lars Hellweg,Peter Sehr,Johannes Ridinger,Olaf Witt,Ina Oehme,Corey J. Herbst-Gervasoni,Jeremy D. Osko,Nicholas J. Porter,David W. Christianson,Nikolas Gunkel,Aubry K. Miller

ChemMedChem（2020）

Cited21Views0WOSBibtex

Methods for the expression, purification, and crystallization of histone deacetylase 6-inhibitor complexes

Jeremy D Osko,David W Christianson

Methods in Enzymology（2019）

Cited12Views0WOSBibtex

Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6

Jeremy D. Osko,David W. Christianson

Biochemistry（2019）

Cited36Views0WOSBibtex

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