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个人简介
Dr. Chang has worked in the field of tumor-initiating cells for more than ten years. After her discovery that tumor-initiating cells are chemo-resistant, and that targeting the EGFR/HER2 pathway can decrease this subpopulation, Dr. Chang has played a key role in demonstrating some of the limitations and mechanisms of tumor-initiating cells (Creighton et al., 2009; Li et al., 2008). Her work is now focused on the mechanisms that regulate TICs, as well as initiating and planning clinical trials that target this critical tumor initiating subpopulation. She is also interested in characterizing the cross-talk between these different pathways that may lead to mechanisms of resistance, and has identified some of the chief regulatory pathways involved in TIC self-renewal. She is a world-renown clinical investigator, credited as one of the first to describe intrinsic chemo-resistance of tumor-initiating cells.
研究兴趣
论文共 595 篇作者统计合作学者相似作者
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Research square (2024)
Chika Ezeana, Xiaohui Yu, Zhihao Wan,Tiancheng He,Tejal Patel,Virginia Kaklamani,Maryam Elmi, Erika Brigmon,Pamela Otto,Kenneth Kist,Lin Wang,Joe Ensor,Heather Speck,Ya-Chen Shih,Bumyang Kim,I-Wen Pan,David Spak,Wei Yang,Jenny Chang,Stephen Wong
Jenny H. Chang,Kelsey Romatoski, Madeline B. Torres, Cyrus John Sholevar,Brenessa Lindeman, Cameron Gaskill, Callisia N. Clark,Flavio Rocha,Taylor S. Riall,Jennifer F. Tseng, Jennifer S. Davids,Timothy M. Pawlik,R. Matthew Walsh
Journal of Gastrointestinal Surgerypp.101896, (2024)
Ann Nguyen Pham, Oluwatoni Okuyemi,Gina F. Milone,Jenny Chang,Argyrios Ziogas,Pranathi Rao,Kenneth Chan
American Journal of Obstetrics and Gynecologyno. 1 (2024): S575-S575
Nir Messer,Ryan C. Ellis,Sara M. Maskal,Jenny H. Chang,Ajita S. Prabhu,Benjamin T. Miller,Lucas RA. Beffa,Clayton C. Petro, Serrgio Mazzola Poli de Figueiredo,Aldo Fafaj,Varisha Essani,Michael J. Rosen
The American Journal of Surgery (2024): 99-104
Abby Gross,Hanna Hong,Mir Shanaz Hossain,Jenny H. Chang,Chase J. Wehrle, Siddhartha Sahai, Joseph Quick, Aleksander Izda,Sayf Said,Samer Naffouje,R. Matthew Walsh,Toms Augustin
Jenny H. Chang,Kimberly P. Woo,Melissa M. Bilec, Maya Camhi, Alexandra I. Melnyk,Abby Gross,R. Matthew Walsh,Sofya H. Asfaw,Ilyssa O. Gordon,Benjamin T. Miller
SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELANDno. 4 (2024): 236-241
The American Surgeonno. 6 (2024): 1397-1405
American Journal of Obstetrics and Gynecologyno. 1 (2024): S201-S201
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作者统计
#Papers: 591
#Citation: 22840
H-Index: 72
G-Index: 147
Sociability: 8
Diversity: 3
Activity: 268
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