My group is interested in problems at the interface of chemistry and biology. We apply chemical principles and techniques to understanding biologically important reactions. We are broadly interested in the way in which nature makes various compounds, the structure and bioactivity of these compounds and in the enzymes that are involved in these pathways. As the work carried out in my group is at the interface of chemistry and biology we use techniques that are drawn from both disciplines including recombinant DNA technology, protein purification and structure determination, organic synthesis, and small molecule structure determination by MS, NMR etc.