基本信息
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Career Trajectory
Bio
Dr. Sahel is known worldwide for his expertise in vision restoration techniques. He has developed several interventions— including stem cell implantation, gene therapy, innovative pharmacologic approaches, and retinal prostheses—for retinitis pigmentosa, other retinal dystrophies, age-related macular degeneration, and other vision impairments that currently are untreatable e.g. Leber Hereditary Optic Neuropathy. Over the past decade he has led pioneering efforts in optogenetic vision restoration, a technique in which cells in the retina are genetically modified to express light sensitive proteins. This therapeutic technique has the potential to help patients who are blind or visually impaired as a result of a genetic defect. His team has developed novel high resolution imaging technologies for retinal and optic nerve conditions. Dr. Sahel also brings a strong neuroscience perspective to ophthalmology research, such as exploring the application of brain-computer interface technology.
Dr. Sahel is a co-inventor on more than 40 patents, several of which have led to start-up companies including Fovea Pharmaceuticals which Dr. Sahel founded and later was acquired by Sanofi Aventis. He also is a scientific co-founder of GenSight Biologics Inc., Pixium Vision Inc., Tilak Healthcare, Chronolife, Prophesee, Sparing Vision,.. He is a member of 11 editorial boards, including the Journal of Clinical Investigation and Science Translational Medicine.
Dr. Sahel is a co-inventor on more than 40 patents, several of which have led to start-up companies including Fovea Pharmaceuticals which Dr. Sahel founded and later was acquired by Sanofi Aventis. He also is a scientific co-founder of GenSight Biologics Inc., Pixium Vision Inc., Tilak Healthcare, Chronolife, Prophesee, Sparing Vision,.. He is a member of 11 editorial boards, including the Journal of Clinical Investigation and Science Translational Medicine.
Research Interests
Papers共 1392 篇Author StatisticsCo-AuthorSimilar Experts
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European Journal of Medical Genetics (2024)
OPHTHALMOLOGY SCIENCEno. 5 (2024)
Thibaud Mathis,Florian Baudin,Anne-Sophie Mariet,Sébastien Augustin, Marion Bricout,Lauriane Przegralek,Christophe Roubeix,Éric Benzenine,Guillaume Blot,Caroline Nous,Laurent Kodjikian,Martine Mauget-Faÿsse,José-Alain Sahel,Robin Plevin, Christina Zeitz,Cécile Delarasse,Xavier Guillonneau, Catherine Creuzot-Garcher, Catherine Quantin,Stéphane Hunot, Florian Sennlaub
The Journal of clinical investigationno. 17 (2024)
Sayan Ghosh,Ruchi Sharma,Sridhar Bammidi,Victoria Koontz,Mihir Nemani,Meysam Yazdankhah, Katarzyna M. Kedziora,Donna Beer Stolz,Callen T. Wallace, Yu-Wei Cheng,Jonathan Franks,Devika Bose,Peng Shang, Helena M. Ambrosino,James R. Dutton,Zhaohui Geng, Jair Montford, Jiwon Ryu,Dhivyaa Rajasundaram,Stacey Hose,Jose-Alain Sahel,Rosa Puertollano,Toren Finkel,J. Samuel Zigler, Yuri Sergeev,Simon C. Watkins,Eric S. Goetzman, Deborah A. Ferrington,Miguel Flores-Bellver,Kai Kaarniranta,Akrit Sodhi,Kapil Bharti,James T. Handa,Debasish Sinha
Nature Communicationsno. 1 (2024): 1-18
International journal of molecular sciencesno. 12 (2024): 6515-6515
Experimental Eye Research (2024): 109826
Yuanyuan Chen,Abhishek Vats,Yibo Xi,Amanda Wolf-Johnston,Owen Clinger,Riley Arbuckle, Chase Dermond,Jonathan Li, Donna Stolze,José-Alain Sahel,Edwin Jackson,Lori Birder
Research square (2024)
José-Alain Sahel,Yannick Le Mer,Frank G. Holz,Joseph Martel, Lisa Olmos de Koo, Mahi Muqit,Daniel Palanker
touchREVIEWS in Ophthalmologyno. 1 (2024)
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Author Statistics
#Papers: 1393
#Citation: 35732
H-Index: 82
G-Index: 131
Sociability: 9
Diversity: 0
Activity: 10
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