Dr. Noble primarily sees patients with dementia but also leads Team Concussion, focusing on sports-related concussion care, and sees patients in a general neurology practice. Dr. Noble is fluent in Spanish and his comprehensive approach to care views the patient within the entire family dynamic, with particular focus on disadvantaged communities.

His professional leadership has been recognized by the American Academy of Neurology, which has selected him to the Emerging Leaders Forum. Dr. Noble is recognized as a leader in neurologic education at Columbia University College of Physicians and Surgeons, as its former clerkship director and a scholar in the Virginia Apgar Teaching Academy. Dr. Noble is also the president of Arts & Minds, a non-profit organization promoting well-being for dementia patients and their caregivers via art-centered experiences.