James C. Yang

基本信息

Career Trajectory

Bio

Dr. Yang is involved in the clinical and scientific study of T-cell adoptive therapy and other immunotherapies to treat melanoma and other cancers. He is particularly interested in expanding these modalities to other cancers such as renal, lung and thyroid cancer and is initiating these clinical protocols. His laboratory efforts have concentrated on the development of novel antigen receptors for T-cells with optimized specificity and efficacy in treating cancers.

Research Interests

Papers共 369 篇Author StatisticsCo-AuthorSimilar Experts

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11P Patritumab deruxtecan (HER3-DXd) in previously treated patients (pts) with advanced EGFR-mutated (EGFRm) NSCLC: Updated safety results from HERTHENA-Lung01

H. Hayashi, Y. Goto,H.A. Yu,P.A. Jänne,J.C-H. Yang,M. Reck,K. Yoh, S-H. Lee,L. Paz-Ares,B. Besse,P. Bironzo,D-W. Kim,Z. Piotrowska,M.L. Johnson, A. Sporchia, K.H. Sullivan,Q. Dong,P. Shrestha, J. Shah,E. Felip

ESMO Open (2024)

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38P Real-world Treatment Patterns and Effectiveness of Subsequent Treatments Following First-Line (1L) Brigatinib for Patients with Anaplastic Lymphoma Kinase Positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) from ALTA-1L

A. Delmonte,M-J. Ahn, S. Ghosh,M.J. Hochmair,T-Y. Yang,J.C-H. Yang,J-Y. Han, K.H. Holmskov, Y. Wu, Y. Wan, M. Lin, J. Kretz, B. Hupf, A.M. Kurec,E. Churchill,R. Fram, C.J. Cabasag, V. Goriya, Y. Zhao,M.R. García Campelo

ESMO Open (2024)

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Translational Insights and Overall Survival in the U31402-A-U102 Study of Patritumab Deruxtecan (Her3-Dxd) in EGFR-mutated NSCLC

H. A. Yu,C. Baik,D. -W. Kim,M. L. Johnson, H. Hayashi, M. Nishio,J. C. -H. Yang,W. -C. Su,K. A. Gold,M. Koczywas,E. F. Smit,C. E. Steuer,E. Felip, H. Murakami,S. -W. Kim, X. Su, S. Sato,P. -D. Fan, M. Fujimura, Y. Tanaka, P. Patel,D. W. Sternberg,D. Sellami,P. A. Jaenne

ANNALS OF ONCOLOGYno. 5 (2024): 437-447

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Amivantamab Plus Lazertinib Versus Osimertinib in First-Line EGFR-mutant Advanced Non-Small Cell Lung Cancer with Biomarkers of High-Risk Disease: a Secondary Analysis from MARIPOSA

E. Felip,B. C. Cho, V Gutierrez,A. Alip,B. Besse, S. Lu,A. I. Spira,N. Girard,R. Califano,S. M. Gadgeel,J. C-H. Yang, S. Yamamoto, K. Azuma,Y. J. Kim, K. -H. Lee,P. Danchaivijitr, C. G. Ferreira,Y. Cheng,M. A. N. Sendur,G. -C. Chang, C. -C. Wang, K. Prabhash, Y. Shinno, D. Stroyakovskiy, L. Paz-Ares, J. R. Rodriguez-Cid, C. Martin, M. R. G. Campelo, H. Hayashi, D. Nguyen, P. Tomasini, M. Gottfried, C. Dooms, A. Passaro, M. Schuler, A. C. Z. Gelatti, S. Owen, K. Perdrizet, S. -H. I. Ou, J. C. Curtin, J. Zhang, M. Gormley, T. Sun, A. Panchal, M. Ennis, E. Fennema, J. M. Bauml, M. Daksh, S. Sethi, S. -H. Lee

ANNALS OF ONCOLOGYno. 9 (2024): 805-816

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Adoptive Transfer of Personalized Neoantigen-Reactive TCR-transduced T Cells in Metastatic Colorectal Cancer: Phase 2 Trial Interim Results

NATURE MEDICINE (2024)

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Identification and Structural Characterization of a Mutant KRAS-G12V Specific TCR Restricted by HLA-A3

Malcolm J. W. Sim,Ken-ichi Hanada, Zachary Stotz,Zhiya Yu,Jinghua Lu,Paul Brennan,Max Quastel,Geraldine M. Gillespie,Eric O. Long,James C. Yang,Peter D. Sun

EUROPEAN JOURNAL OF IMMUNOLOGY (2024)

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Salvage Metastasectomy after Adoptive Cell Transfer for Melanoma: Long-Term Updates

Aaron J. Dinerman, Alexandra M. Gustafson,Ali T. Elsaadi,Donald White,David S. Schrump,Chuong D. Hoang,Jonathan M. Hernandez,Mei Li Kwong,James C. Yang,Stephanie Goff,Steven A. Rosenberg,Nicholas D. Klemen

ANNALS OF SURGICAL ONCOLOGY（2024）

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Lifileucel: FDA-approved T-cell therapy for melanoma

Mei Li M Kwong,James C Yang

The oncologistno. 8 (2024): 648-650

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PP01.24 FURVENT: Phase 3 Trial Testing Furmonertinib Vs Chemotherapy As First-Line Treatment for Advanced NSCLC with EGFR Exon 20 Insertions (FURMO-004)

Alexander Spira,Byoung Chul Cho,Enriqueta Felip,Edward B. Garon,Koichi Goto,Melissa Johnson,Natasha Leighl,Antonio Passaro, David Planchard,Sanjay Popat,James Yang, Xiaoqian Lu, Yong Jiang,Jack Huang,Morgan Lam, Marcin Kowanetz, Shirley Wang,John Le,Jerry Y. Hsu, Cai-Cun Zhou

Journal of Thoracic Oncologyno. 7 (2024): e17-e18

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Papers共 369 篇Author StatisticsCo-AuthorSimilar Experts