The main field of investigation of Valerio Vercesi has been High Energy Physics, for which he worked most of the time at CERN Laboratories in Geneva (CH), including a three-year Fellowship, won after a national selection. He participated in the discovery of the Intermediate Vector Bosons, demonstrating the unification of the fundamental electromagnetic and weak nuclear forces, which won the Nobel Prize to Carlo Rubbia. He contributed to build the forward-backward tracking detectors of the UA2 experiment, and he was responsible for the track reconstruction software, He worked also on the real-time imaging of the events recorded by the experiment, allowing for a fast identification of potentially interesting candidates.