He has reported that angiotensin II type 1 receptor is involved in mechanical stress-induced cardiac hypertrophy and has recently reported novel mechanisms of heart failure such as ischemia, inflammation and aging. He has also studied cardiac development and has isolated cardiac specific homeobox protein Nkx2.5. He has published more than 700 papers on peer-review journals including Natute, Cell and Nature Medicine.
Licensure and Certification:
1982 Permanent License of Practice of Medicine, Japan
1989 National Board of Medicine
1996 National Board of Cardiology
2001 Fellow of American Heart Association
2010 Fellow of ISHR
2013 Fellow of European Society of Cardiology
Awards and Honors:
1985 Gold Medal for Erwin von Balz Preiz (first prize)
1988 Japan Heart Foundation Research Grant for Young Investigators.
1990 American College of Cardiology/Merck Award
1991-1993 The Medical Foundation Fellowship Award
1993 Louis N. Katz Basic Science Research Prizes for Young Investigators(Finalist), American Heart Association
1997 Okamoto Award for Young Investigators, Award of Medical Society of Tokyo University
1998 Award of Medical Society of Tokyo
2000 Sato Award of Japanese Circulation Society, Takamine Jyokichi Research Award
2003 Award of Japanese Society of Molecular Medicine, Outstanding Investigator Prize of the International Society of Heart Research
2004 Academic Award of the Mochida Memorial Foundation
2010 Gold Medal for Erwin von Balz Preiz (first prize), President’s Distinguished Lectures of the ISHR Award
2012 Takamine Jyokichi Award