Prof. Hsiu-Hsi Chen is an expert in evaluation of intervention program, with emphasis on population-based cancer screening and also universal vaccination program, by using a series of complex statistical modelling to deal with several thorny issues that cannot be solved by classical approaches. These include the development of different health economic decision models for cancer screening program and also vaccination program and prophylactic treatment. The recent statistical publications on the methodology of applying stochastic process to evaluation of cancer screening model published in JASA and Biometrics with Bayesian and non-Bayesian approach have facilitated the development of health economic decision models. A series of original articles cost-effectiveness (benefit) analysis based on these models have been published in international peer review articles. Regarding international academic cooperation, Professor Chen has taken the presidency of the international Asian Cancer Screening Conference (Network) held annually since 2004. As far as collaborative research in Western countries is concerned, the long-lasting collaboration with Sweden (Falun Central Hospital), the USA (American Cancer Society), United Kingdom (Wolfson Institute of Preventive Medicine), and also Finland (School of Public Health, University of Tampere) where Professor Chen was awarded the Finland Distinguished Professor (FIDIPRO) issued by the Academy of Finland between 2007 and 2009.