He was a Pelican Cancer Foundation Research Fellow followed by a MRC Clinician Research Training fellowship at University College London at which time a number of imaging and focal therapy trials were started. His research interests are in Health Technology Evaluation including multi-parametric MRI, Histoscanning, Tissue Type Imaging, as well as therapeutic interventions such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and radiofrequency ablation. He has completed numerous phase I/II clinical trials evaluating the role of focal therapy in prostate cancer and is lead PI and Co-PI in a number of multicentre trials including the UK NIHR-HTA funded study NCRN PROMIS study evaluating the role of multi-parametric MRI in men with a raised PSA using Template Prostate Mapping as the reference standard as well as NCRN INDEX, a multicentre focal therapy study using HIFU with 3 year follow-up and NCRN FORECAST. He previously held a £1.2M MRC Clinician Scientist Fellowship for 5 years and currently holds a £2M Senior Clinical Research Fellowship from the Wellcome Trust. His total grant income is £5M as lead applicant and £8M in total as co-applicant.