Gonçalo Castelo-Branco is a Professor of Glial Cell Biology at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, Stockholm, Sweden. Gonçalo received is PhD in Medical Biochemistry in 2005, with Prof. Ernest Arenas of the Karolinska Institutet, on development of dopaminergic neurons and neural stem differentiation. He completed post-doctoral fellowships first with Assoc. Professor Ola Hermanson (Karolinska Institutet) and then with Prof. Tony Kouzarides (University of Cambridge, United Kingdom), working in neural stem cells and pluripotent stem cells, and chromatin. Gonçalo started his lab in 2012, focusing on the molecular mechanisms defining the epigenetic state of cells of the oligodendrocyte lineage. His research group is particularly focused on how interplay between transcription factors, non-coding RNAs and chromatin modifying enzymes contributes to the transition between epigenetic states in oligodendrocyte lineage cells- with the aim to design epigenetic based-therapies to induce regeneration (remyelination) in demyelinating diseases, such as multiple sclerosis.