Georgios Kosmidis - Leiden University Medical Centre

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论文共 22 篇作者统计合作学者相似作者

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BRD-810 is a Highly Selective MCL1 Inhibitor with Optimized in Vivo Clearance and Robust Efficacy in Solid and Hematological Tumor Models

Ulrike Rauh,Guo Wei,Michael Serrano-Wu,Georgios Kosmidis,Stefan Kaulfuss,Franziska Siegel,Kai Thede,James McFarland,Christopher T Lemke,Nicolas Werbeck,Katrin Nowak-Reppel, Sabine Pilari,Stephan Menz, Matthias Ocker, Weiqun Zhang, Kyle Davis, Guillaume Poncet-Montange,Jennifer Roth, Douglas Daniels,Virendar K Kaushik,Brian Hubbard,Karl Ziegelbauer,Todd R Golub

Nature cancerno. 10 (2024): 1479-1493

引用1浏览0WOS引用

Rapidly cleared MCL1 inhibitor TTX-810 showing robust efficacy in preclinical tumor models with no effects on cardiomyocytes in vitro and in vivo

Ulrike Rauh,Virendar Kaushik,Sabine Pilari,Georgios Kosmidis,Michael Serrano-Wu,Guo Wei, Weiqun Zhang,Stefan Kaulfuss,Kai Thede, Guillaume Poncet-Montange,Douglas Daniels,Christopher T. Lemke,Brian Hubbard,Todd R. Golub

MOLECULAR CANCER THERAPEUTICSno. 12 (2023)

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Abstract LB_A01: Rapidly Cleared MCL1 Inhibitor TTX-810 Showing Robust Efficacy in Preclinical Tumor Models with No Effects on Cardiomyocytes in Vitro and in Vivo

Ulrike Rauh, Virendar K. Kaushik,Sabine Pilari,Georgios Kosmidis, Michael H. Serrano‐Wu,Guo Wei, Weiqun Zhang,Stefan Kaulfuß,Kai Thede, G. Poncet-Montange,Douglas S. Daniels,Christopher T. Lemke,Bryn Hubbard, Todd R. Golub

Molecular cancer therapeuticsno. 12_Supplement (2023): LB_A01-LB_A01

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Assessment of drug-induced structural toxicity in human iPSC-derived cardiomyocytes: An image-based approach to complement traditional in vitro safety studies

Brigitta R. Szabo,Georgios Kosmidis,Paul G. A. Volders,Elena Matsa

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2023)

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Maturation of Hipsc-Derived Cardiomyocytes Promotes Adult Alternative Splicing of SCN5A and Reveals Changes in Sodium Current Associated with Cardiac Arrhythmia

Giulia Campostrini,Georgios Kosmidis,Dorien Ward-van Oostwaard,Richard P. Davis,Loukia Yiangou,Daniele Ottaviani,Christiaan C. Veerman,Hailiang Mei,Valeria V. Orlova,Arthur A. M. Wilde,Connie R. Bezzina,Arie O. Verkerk,Christine L. Mummery,Milena Bellin

Cardiovascular research（2022）

引用10浏览0WOS引用

Maturation of Hipsc-Derived Cardiomyocytes in Cardiac Microtissues Promotes Adult Alternative Splicing of Sodium Channel Revealing Mutation Effects Associated with Cardiac Arrhythmia

G. Campostrini,D. Ward-Van Oostwaard,G. Kosmidis,A. O. Verkerk,C. R. Bezzina,C. L. Mummery,M. Bellin

Cardiovascular researchno. Supplement_1 (2022)

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Genetic correction of the W156X mutation in a patient- specific hiPSC line carrying compound heterozygous mutations in the SCN5A gene

G. Kosmidis,M. Bellin,A. Verkerk, Richard P. Davis,C. Bezzina,C. Mummery

semanticscholar（2017）

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Chapter 2 Immaturity of stem-cell derived cardiomyocytes : fatal fl aw or soluble problem

Christiaan C. Veerman,Georgios Kosmidis,Christine L. Mummery

semanticscholar（2017）

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PGC-1α and reactive oxygen species regulate hESC-derived cardiomyocyte function

Matthew J Birket,Georgios Kosmidis,Simona Casini,David A Elliott, Akos, A Gerencser,Antonius Baartscheer,Cees Schumacher,Pier G Mastroberardino,Andrew G Elefanty,Ed G Stanley,Christine L Mummery

semanticscholar（2017）

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