My research interests include the determinants of mental and cognitive wellbeing, and the use of data at-scale. I am Director of Dementias Platform UK, an MRC-funded public-private partnership focused on accelerating research into the early detection and treatment of dementia. I am Principal Investigator for the BrainWaves study of adolescent mental health, and for the Caerphilly Prospective Study (CaPS). I hold a visiting professorship at Imperial College London and an honorary professorship at the University of Hong Kong. I am a member of the SAIL Scientific Advisory Board and the KREMBIL Research Institute Scientific Advisory Board. I was a member of the UK Biobank steering group between 2010 and 2022.