Gaelle Friocourt - GGB, Univ Brest | 人才画像

基本信息

Career Trajectory

Bio

We work on cortical development with a focus on ARX, a gene involved in the development of GABAergic neurons. Using mouse models and iPS technology, we study the role of this gene in cognitive and fine motor functions such as language and prehension. In another project, we are investigating the effect of cystathionine-beta synthase (CBS) overexpression in brain function. The gene dosage of this enzyme appears critical in homocystinuria and Down syndrome.

Research Interests

Papers共 52 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

New insights into the regulation of Cystathionine beta synthase (CBS), an enzyme involved in intellectual deficiency in Down syndrome

Pierre Conan,Alice Leon,Noeline Caroff,Claire Rollet,Loubna Chair,Jennifer Martin,Frederic Bihel,Olivier Mignen,Cecile Voisset,Gaelle Friocourt

FRONTIERS IN NEUROSCIENCE (2023): 1110163

Cited1Views0WOSBibtex

Bypassing Mendel’s First Law: Transmission Ratio Distortion in Mammals

Gaëlle Friocourt,Aurore Perrin,Paul A. Saunders,Elvira Nikalayevich,Cécile Voisset,Charles Coutton,Guillaume Martinez,Frédéric Morel

International Journal of Molecular Sciencesno. 2 (2023): 1600

Cited0Views0Bibtex

Oligodendrocyte Lineage is Severely Affected in Human Alcohol-Exposed Foetuses

Florent Marguet,Mélanie Brosolo,Gaëlle Friocourt,Fanny Sauvestre,Pascale Marcorelles,Céline Lesueur,Stéphane Marret,Bruno J. Gonzalez,Annie Laquerrière

Acta Neuropathologica Communicationsno. 1 (2022)

Cited3Views0WOSBibtex

P53, A Victim of the Prion Fashion

Olivier Billant,Gaëlle Friocourt,Pierre Roux,Cécile Voisset

Cancersno. 2 (2021)

Cited7Views0WOSBibtex

Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation

Bamia Aline,Sinane Maha,Naït-Saïdi Rima,Dhiab Jamila,Keruzoré Marc, Bertho Agathe, University of Dundee, Univ. Lille,Blondel Marc,Trollet Capucine,Simonelig Martine,Friocourt Gaëlle,Béringue Vincent,Bihel Frédéric,Voisset Cécile

Neurotherapeutics（2021）

Cited5Views0WOSBibtex

Mechanism of Cystathionine-Β-synthase Inhibition by Disulfiram: the Role of Bis(n,n-Diethyldithiocarbamate)-copper(ii)

Karim Zuhra,Theodora Panagaki,Elisa B. Randi,Fiona Augsburger,Marc Blondel,Gaelle Friocourt,Yann Herault,Csaba Szabo

Biochemical Pharmacology（2020）

Cited23Views0WOSBibtex

Cbs Overdosage is Necessary and Sufficient to Induce Cognitive Phenotypes in Mouse Models of Down Syndrome and Interacts Genetically with Dyrk1a

Damien Marechal,Veronique Brault,Alice Leon, Dehren Martin,Patricia Lopes Pereira,Nadege Loaec,Marie-Christine Birling,Gaelle Friocourt,Marc Blondel,Yann Herault

Human molecular genetics online/Human molecular genetics（2019）

Cited40Views0WOSBibtex

Author Statistics

Co-Author

Co-Institution

D-Core

合作者
学生
导师

No result temporarily, you can search similar Scholar with the same research interest

Data Disclaimer

The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn