My research interests are in the area of metabolomics, both methods development and applications focusing investigations of human health and diseases. Our methods development, utilizing nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) techniques, is focused on the analysis of metabolites in complex biological mixtures from humans, animal models and cell lines. We also combine NMR and MS techniques to exploit their combined strength to unravel the biological complexity and identify and quantify unknown metabolites. We are particularly interested in enhancing the NMR’s detection sensitivity and resolution with a view to expand the pool of quantifiable metabolites for metabolomics applications. As a part of this aim, we develop and utilize smart isotope tags that possess dual characteristics – stable isotope for NMR’s sensitivity and permanent charge for MS’s sensitivity- and enable exploiting the combined strength of two bioanalytical platforms.