Mark A. Frye, M.D., has a research focus on genomics, brain imaging, and neuroendocrinology of mood disorders and alcoholism, complementing his clinical interests in bipolar disorder, depression and alcoholism.

Dr. Frye receives research support from the National Institute of Mental Health, Mayo Clinic's Samuel C. Johnson Genomics of Addiction Program, SC Johnson Giving, Inc., the Marriott family and the Mayo Clinic Center for Individualized Medicine. He has also received funding from the National Institute on Alcohol Abuse and Alcoholism.