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Bio
Dr. Henn applies imaging, animal studies, and genetics to understanding the bases of depression and schizophrenia. His group is attempting to use animals modeling depression to identify the genes altered by aversive experience, which may contribute to depression. They are also beginning clinical tests with patients using deep brain stimulation (DBS) to inhibit the habenula, a group of neurons associated with pain processing and negative feedback encoding, as a potential treatment for depression. The successful move from the animal model to working on patients suggests this model may help to identify the pathophysiology of depression. The group feels this lies in altered excitatory transmission in the cortex and has patented a class of drugs that may reverse this.
Research Interests
Papers共 180 篇Author StatisticsCo-AuthorSimilar Experts
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Journal of Comparative Neurologyno. 12 (2021): 3194-3205
Lutz Frölich,Oliver Peters,Piotr Lewczuk,Oliver Gruber,Stefan J. Teipel,Hermann J. Gertz, Holger Jahn,Frank Jessen,Alexander Kurz,Christian Luckhaus,Michael Hüll,Johannes Pantel,Friedel M. Reischies,Johannes Schröder,Michael Wagner,Otto Rienhoff,Stefanie Wolf,Chris Bauer,Johannes Schuchhardt,Isabella Heuser,Eckart Rüther,Fritz Henn,Wolfgang Maier,Jens Wiltfang,Johannes Kornhuber
Steffen Wolfsgruber,Frank Jessen,Alexander Koppara,Luca Kleineidam,Klaus Schmidtke,Lutz Froelich,Alexander Kurz,Stefanie Schulz,Harald Hampel,Isabella Heuser,Oliver Peters,Friedel M. Reischies,Holger Jahn,Christian Luckhaus,Michael Huell,Hermann-Josef Gertz,Johannes Schroeder,Johannes Pantel,Otto Rienhoff,Eckart Ruether,Fritz Henn,Jens Wiltfang,Wolfgang Maier,Johannes Kornhuber,Michael Wagner
Joseph T Coyle, Stephan Heckers, Frances Macneil,Ross J Baldessarini,Floyd E Bloom,David L Braff, Kenneth C Davis,Raymond J Dolan,Ellen Frank,James C Harris,Fritz A Henn,Kenneth S Kendler, C Kessler,David J Kupfer,Herbert Y Meltzer, Ries Merikangas, M Owen, L Rapoport,Alan F Schatzberg,Ronald J Steingard,Ming T Tsuang,Myrna M Weissman,Kenneth B Wells,Charles F Zorumski
mag(2015)
Cited23Views0Bibtex
23
0
Alexander Koppara,Steffen Wolfsgruber,Luca Kleineidam,Klaus Schmidtke,Lutz Frölich,Alexander Kurz,Stefanie Schulz,Harald Hampel,Isabella Heuser,Oliver Peters,Friedel M. Reischies, Holger Jahn,Christian Luckhaus,Michael Hüll,Hermann-Josef Gertz,Johannes Schröder,Johannes Pantel,Otto Rienhoff,Eckart Rüther,Fritz Henn
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Author Statistics
#Papers: 180
#Citation: 10351
H-Index: 53
G-Index: 98
Sociability: 7
Diversity: 0
Activity: 0
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