The focus of my research is to develop and evaluate new image processing methods, algorithms, and software tools for the analysis of medical images. This includes the image-based extraction of clinically relevant parameters and biomarkers describing the morphology and function of organs. In doing so, we aim to support clinical studies and preclinical research as well as developing and improving computer-aided diagnosis and patient-specific prediction models with a special focus on, but not limited to, the human brain. Additionally, we are developing advanced machine learning models for various diseases using multi-modal data sources, not limited to image-based features.