Her major scientific interest is focused on translational research involving the design of new diagnostic strategies for human cancer. Firstly, developing several types of new immunoassays to better evaluate the presence of circulating tumor antigens potentially useful in monitoring human cancer. Recent research interests have broadened to include the investigation of different pro-inflammatory cytokines involved in cancer and to studying novel cancer diagnostic strategies, with emphasis being placed on the identification and development of molecular diagnostics tools. More recently, her scientific interest is dedicated to proteomics studies for the discovery of biomarkers of diagnostic potential for early diagnosis and discrimination of several neurodegenerative and cardiovascular diseases and functional genomic and proteomic approaches in cancer and neurodegenerative diseases research.
Dr Guadagni has been and is the principal investigator and/or coordinator of numerous studies granted by governmental and scientific organizations and is a member of several national and international scientific societies and of Editorial Boards and reviewer of several Peer-Reviewed Scientific Journals.
Dr. Guadagni is author of 134 papers published in international journals for a total Impact Factor of 500,9, with an Index H of 26, more than 20 chapters book and more than 300 abstracts presented at national and international meetings.