Regular arrangement of catalysts in reactors decouples the scale dependent and independent phenomena, such as intrinsic kinetics, thermodynamics, mass and heat transport and hydrodynamics. This allows their independent optimization so that all rate processes in a reactor are in balance and the catalyst is used in the way it was designed for. Structuring ranges from the molecular to the reactor scale in a hierarchical way. Microscopically zeolites, MOFs and well defined clusters are used. Macroscopically one should think of monoliths, foams, corrugated packing etc. Combined with multifunctional operation this approach can give a large boost to process intensification. Radial heat transport in reactor packings is a big challenge and subject of study.