Dr Eric R. Gamazon develops and applies genomic and computational methods to investigate the genetic architecture of complex traits. His laboratory is an interdisciplinary group with expertise in computational genomics and molecular biology. He is interested in what can be learned from DNA sequence and multi-omics data about disease mechanism, therapeutic intervention, molecular evolution, and genome function. An ongoing project involves understanding gene regulation across tissues and cell types. He utilizes large-scale DNA biobank data linked to phenome-scale data, along with data science and computation, to identify genes involved in human health and disease in diverse populations, to discover novel biomarkers, and to enable a comprehensive systems view of the disease phenome.