Dr. Simoes is working with the World Health Organization for the management of common pediatric conditions in developing countries (Integrated Management of Childhood Illness) and studies the epidemiology, pathogenesis, and prevention of the short- and long-term effects of respiratory syncytial virus infection in children. Dr. Simoes has played a significant role in the World Health Organization's initiative to reduce childhood and infant mortality throughout the world with the development of a strategy called "Integrated Management of Childhood Illness." He has worked on this initiative since 1989, including testing and implementing its guidelines in many countries throughout Africa, Asia, and Europe.