My research focuses on Huntington's disease, a fatal, autosomal dominantly inherited neurodegenerative disease that usually begins in mid-adult life and produces cognitive, behavioural and motor decline.

No cure or disease-slowing treatment exists for HD, but uniquely among prevalent neurodegenerative diseases, Huntington's disease (HD) is fully penetrant and monogenic. This has enabled the development of many promising therapeutic options designed to target known pathogenic pathways in HD.