He conducts both basic and clinical research in the area of ischaemic heart disease, heart failure, cardioprotection and cardiac MRI. His research focus is on discovering novel therapies for protecting the heart against the detrimental effects of acute ischaemia/reperfusion injury in order to prevent the onset of heart failure. He uses a translational approach to cardioprotection ranging from cellular and animal models of acute IRI to proof-of-concept clinical studies in acute myocardial infarction and cardiac bypass surgery patients, and finally to large multi-center randomised clinical trials focused on clinical outcomes. He is also interested in both small animal and clinical cardiac PET and MRI imaging in the context of acute myocardial infarction and cardioprotection. Prof Hausenloy has been PI on over 20 research grants, and he has authored over 240 papers and his H-index is 78. In 2018 he was named Highly Cited Researcher, and in 2019 he received the Distinguished Professorship entitled Lee Kong Chian Centennial Professor in Cardiovascular Research, National University Singapore.