As an Assistant Professor at Johns Hopkins University School of Medicine, I study the subjective qualities, behavioral effects, and therapeutic potential of psychedelic substances. I also study self-transcendent experiences in general. My research provides an empirical, 21st-century update to William James’ The Varieties of Religious Experience, using: 1) psychometric survey instruments, 2) computational linguistic analysis, 3) neuroimaging, 4) neurostimulation, and 5) psychopharmacology.