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个人简介
He has authored over 450 scientific publications and has supervised more than 55 PhD graduates. He is an international authority in genome sciences, with a particular focus on the function of macrophages—specialised cells of the immune system involved in innate immunity against infections, inflammatory disease and cancer. David’s research focusses on macrophages in normal growth, development and physiology, infectious disease resistance and progression and complications of inflammation. His lab investigates mechanisms that regulate the biological functions of macrophages and explores avenues to boost their normal function and/or limit the damage they cause in inflammatory and infectious diseases. He is also interested in the genetic variations in macrophage function between individuals that contribute to susceptibility to inflammatory and infectious diseases. David has been elected to Fellowships in the Royal Society of Edinburgh, the UK Academy of Medical Sciences and the Royal Society of Biology. Since 2000, he has been a leading member of the FANTOM Consortium, which has made extensive contributions to mammalian genome and transcriptome annotation. David has a 35 year track record of attracting major strategic funding (CRC for Chronic Inflammatory Disease, ARC Special Research Centre in Australia; BBSRC Institute Strategic Programmes, Wellcome Trust Centres, UK Agritech Centre and Bill and Melinda Gates Centre Foundation in the UK) as well as continuous research project funding from NHMRC, ARC, BBSRC, MRC and the Wellcome Trust. "I trained as a metabolic biochemist at the Australian National University, and was very fortunate to have a great mentor in Dr Maurie Weidemann. Throughout my career, I have tried to mentor others with the same level of enthusiasm and support given to me. Being a biological scientist in the early 21st century is very much like being a physical scientist in the early 20th century. Each day brings new technologies and completely unexpected discoveries. I believe that the most novel breakthroughs and advances in human medicine and biotechnology come from basic discovery science, and fundamental understanding of macrophage biology has been my research focus for the whole of my career. That said, the applications of that understanding to human disease are clear, especially in the areas of tissue repair and regenerative medicine, and I am committed to pursuing those applications to benefit patients."
研究兴趣
论文共 397 篇作者统计合作学者相似作者
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Phillip J Whiley,Ojas V A Dixit, Mukta Das Gupta,Hardip R Patel, Guoyan Zhao,Susan Connor,Kim Summers,David A Hume,Paul Pavli,Claire L O'Brien
biorxiv(2024)
Thi Viet Trinh Dang, Kevin R. Gillinder,Quan Nguyen, Onkar Mulay, Tuan Vo, Ahmed M. Mehdi, Chenhao Zhou, Andrew J. Brooks, Kiran Asplett, Graham R. Leggatt,David A. Hume,Ian H. Frazer,Janin Chandra
Cancer Immunology Researchno. 10_Supplement (2024)
AJP Endocrinology and Metabolismno. 2 (2024): E149-E165
Mary O’Keeffe,Sam A Booker, Darren Walsh,Mosi Li, Chloe Henley, Laura Simões de Oliveira, Mingshan Liu, Xingran Wang, Maria Banqueri-Lopez,Katherine Ridley, Kosala Dissanyake, Cristina Martinez-Gonzales, Kirsty Craigie,Deepali Vasoya, Tom Leah, Xin He,David A Hume,Ian Duguid,Matthew F Nolan,Jing Qiu,David J. A. Wyllie,Owen R Dando, Alfredo Gonzales-Sulsar,Jian Gan,Clare Pridans,Peter C Kind,Giles E Hardingham
crossref(2024)
crossref(2023)
crossref(2023)
JOURNAL OF BONE AND MINERAL RESEARCH (2023): 139-139
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Abigail K. Grootveld,Wunna Kyaw, Veera Panova,Angelica W. Y. Lau, Emily Ashwin, Guillaume Seuzaret,Rama Dhenni, Nayan Deger Bhattacharyya,Weng Hua Khoo,Mate Biro,Tanmay Mitra,Michael Meyer-Hermann,Patrick Bertolino,Masato Tanaka,David A. Hume,Peter I. Croucher,Robert Brink,Akira Nguyen,Oliver Bannard,Tri Giang Phan
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作者统计
#Papers: 397
#Citation: 27418
H-Index: 75
G-Index: 158
Sociability: 8
Diversity: 3
Activity: 154
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