Darcie J. Miller - Departments of Structural Biology, St. Jude Children's Research Hospital

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论文共 59 篇作者统计合作学者相似作者

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Selective CK1α Degraders Exert Antiproliferative Activity Against a Broad Range of Human Cancer Cell Lines

NATURE COMMUNICATIONSno. 1 (2024)

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EMhub: a Web Platform for Data Management and On-the-fly Processing in Scientific Facilities

Jose M de la Rosa-Trevin,Grigory Sharov, Stefan Fleischmann,Dustin Morado, John C Bollinger,Darcie J Miller,Daniel S Terry,Scott C Blanchard, Israel S Fernandez,Marta Carroni

Acta crystallographica Section D, Structural biologyno. Pt 11 (2024): 780-790

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PROTAC-mediated Activation, Rather Than Degradation, of a Nuclear Receptor Reveals Complex Ligand-Receptor Interaction Network

Andrew D Huber,Wenwei Lin,Shyaron Poudel,Darcie J Miller,Taosheng Chen

Structure (London, England 1993) (2024)

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Principles of Paralog-Specific Targeted Protein Degradation Engaging the C-degron E3 KLHDC2

Daniel C Scott,Suresh Dharuman,Elizabeth Griffith,Sergio C Chai, Jarrid Ronnebaum,Moeko T King,Rajendra Tangallapally, Chan Lee,Clifford T Gee,Lei Yang,Yong Li, Victoria C Loudon,Ha Won Lee, Jason Ochoada,Darcie J Miller, Thilina Jayasinghe,Joao A Paulo, Stephen J Elledge,J Wade Harper,Taosheng Chen,Richard E Lee,Brenda A Schulman

Nature communicationsno. 1 (2024): 8829-8829

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Chemical Manipulation of an Activation/inhibition Switch in the Nuclear Receptor PXR

Efren Garcia-Maldonado,Andrew D. Huber,Sergio C. Chai,Stanley Nithianantham,Yongtao Li,Jing Wu,Shyaron Poudel,Darcie J. Miller,Jayaraman Seetharaman,Taosheng Chen

NATURE COMMUNICATIONSno. 1 (2024)

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A Bromodomain-Independent Mechanism of Gene Regulation by the BET Inhibitor JQ1: Direct Activation of Nuclear Receptor PXR

Andrew D. Huber,Shyaron Poudel,Jing Wu,Darcie J. Miller,Wenwei Lin,Lei Yang,Monicah N. Bwayi,Mary Ashley Rimmer,Rebecca R. Florke Gee,Jayaraman Seetharaman,Sergio C. Chai,Taosheng Chen

NUCLEIC ACIDS RESEARCHno. 4 (2024): 1661-1676

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Human IFT-A complex structures provide molecular insights into ciliary transport

Meiqin Jiang,Vivek Reddy Palicharla,Darcie Miller,Sun-Hee Hwang,Hanwen Zhu,Patricia Hixson,Saikat Mukhopadhyay,Ji Sun

Cell research（2023）

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Ligand Flexibility and Binding Pocket Malleability Cooperate to Allow Selective PXR Activation by Analogs of a Promiscuous Nuclear Receptor Ligand

Andrew D. Huber,Shyaron Poudel,Yongtao Li,Wenwei Lin,Jing Wu,Darcie J. Miller,Taosheng Chen

STRUCTUREno. 12 (2023)

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Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein

Wenwei Lin,Andrew D. Huber,Shyaron Poudel,Yongtao Li,Jayaraman Seetharaman,Darcie J. Miller,Taosheng Chen

Proc Natl Acad Sci U S A（2023）

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Structure-guided approach to modulate small molecule binding to the promiscuous pregnane X receptor

Andrew D. Huber,Wenwei Lin,Shyaron Poudel,Yongtao Li,Jayaraman Seetharaman,Darcie J. Miller,Taosheng Chen

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2023)

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