基本信息
浏览量:8
职业迁徙
个人简介
Research Summary
Our laboratory develops new tools and genomic approaches for molecular screening and diagnostics and the study of disease pathogenesis. We couple experimental and computational techniques to fully integrate all steps of highly multiplexed molecular assays, which include nucleic acid extraction from small and challenging clinical samples (e.g., dried blood spots, plasma), targeted (multi-gene panels, exome, microarrays) and genome sequencing, detection of rare single nucleotide and copy number variants, and data interpretation in the context of clinical findings. We use laboratory automation to increase assay precision and speed, and work on implementing these techniques into rapid disease screening and diagnostics. Our lab is located in a highly translational setting next to the Yale DNA Diagnostic Laboratory. We work closely with the Yale Center for Genome Analysis (YCGA) and collaborate with clinical colleagues and researcher at Yale and other institutions. Please read here about our most recent projects.
We are interested in collaborations of all sorts including clinical medicine, genetics and genomics, biochemistry, technology development, chemical and electrical engineering, statistics and computational sciences. We seek highly motivated students and postdoctoral candidates to join a multi-disciplinary team of experimental and computational scientists in a highly translational setting at the Yale Genetics Department. Please feel free to contact curt.scharfe@yale.edu for open positions.
Our laboratory develops new tools and genomic approaches for molecular screening and diagnostics and the study of disease pathogenesis. We couple experimental and computational techniques to fully integrate all steps of highly multiplexed molecular assays, which include nucleic acid extraction from small and challenging clinical samples (e.g., dried blood spots, plasma), targeted (multi-gene panels, exome, microarrays) and genome sequencing, detection of rare single nucleotide and copy number variants, and data interpretation in the context of clinical findings. We use laboratory automation to increase assay precision and speed, and work on implementing these techniques into rapid disease screening and diagnostics. Our lab is located in a highly translational setting next to the Yale DNA Diagnostic Laboratory. We work closely with the Yale Center for Genome Analysis (YCGA) and collaborate with clinical colleagues and researcher at Yale and other institutions. Please read here about our most recent projects.
We are interested in collaborations of all sorts including clinical medicine, genetics and genomics, biochemistry, technology development, chemical and electrical engineering, statistics and computational sciences. We seek highly motivated students and postdoctoral candidates to join a multi-disciplinary team of experimental and computational scientists in a highly translational setting at the Yale Genetics Department. Please feel free to contact curt.scharfe@yale.edu for open positions.
研究兴趣
论文共 77 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
METABOLITESno. 1 (2024)
Honey V. Reddi, Matthew R. Avenarius,Lora J.H. Bean,Hunter Best,Saurav Guha, Benjamin E. Kang,Curt Scharfe,Bryce A. Seifert,Erin Wakeling
Genetics in Medicinepp.101100, (2024)
2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)pp.769-772, (2023)
引用0浏览0EIWOS引用
0
0
International journal of neonatal screeningno. 4 (2023): 63-63
BIOSENSORS-BASELno. 3 (2023)
Neeru Gandotra,Gang Peng,Irina Tikhonova, Caroline Storer,Justin Mak,Guilin Wang,Tina Cowan,Curt Scharfe
Genetics in Medicine Openno. 1 (2023): 100599-100599
加载更多
作者统计
#Papers: 76
#Citation: 5540
H-Index: 27
G-Index: 51
Sociability: 6
Diversity: 3
Activity: 26
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn