Johannes Crezee

1986: MSc Experimental Physics, Free University, Amsterdam 1988-1992 Project representation of blood flow in thermal models in hyperthermia treatment planning, UMC Utrecht 1993: PhD thesis ‘verification of thermal models’, University of Utrecht 1992-1999 Development and clinical application of an interstitial hyperthermia system with spatial power control for improved temperature uniformity in the tumor, UMC Utrecht 2000-now Hyperthermia research at Department of Radiotherapy of the Academic Medical Center Amsterdam: system design, treatment planning, comercialisation 4 antenna locoregional hyperthermia system for pelvic tumors Dr Crezee published >230 papers in peer reviewed journals, H-index: 51 (google scholar)/ 41 (WebOfScience). awards: - Dr. BB Singh Award, 2010, Indian Association of Hyperthermic Oncology and Medicine - ESHO-Pyrexar award 2018, European Society for Hyperthermic Oncology - George M. Hahn award 2023, Society for Thermal Medcine Coordinator of: - EU H2020 European Training Network (H2020-MSCA-ITN-2020-955625) HYPERBOOST: Hyperthermia boosting the effect of Radiotherapy Project leader of research projects granted by the Dutch Cancer Society Koningin Wilhelmina Fonds (KWF): - Development of a dual modality hyperthermia technique for esophageal cancer (2002-2622) - Clinical validation and application of hyperthermia treatment planning (2006-3484) - Improved temperature reconstruction technique based on treatment planning to be used during superficial hyperthermia (2007-3841) - Improved treatment delivery using treatment planning and MRI data (2010-4660) - Active hot spot suppression to improve thermal dose and clinical outcome of locoregional hyperthermia treatments (2012-5393). - Improved bladder temperature monitoring during hyperthermia treatments (2012-5539). - MRI based hyperthermia treatment planning for improved hyperthermia delivery in cervical cancer patients (2014-7197), J Crezee, ALHMW van Lier, LJA Stalpers. - Development of treatment planning to optimize clinical effectiveness of hyperthermic intraperitoneal chemotherapy in colorectal cancer patients (2017-10595) J Crezee, NAP Franken, HP Kok, PJ Tanis - Improving therapeutic effectiveness and reducing toxicity of HIPEC for colorectal peritoneal metastases (PMCRC) by applying “step-up” heating (2021-13420) J Crezee, AL Oei, HP Kok, J Tuynman co-PI KWF projects: - Irreversible electroporation for locally advanced pancreatic cancer; optimization of clinical treatment by advanced treatment planning (2014-7244), MGH Besselink, J Crezee, TM van Gulik. - Hyperthermia induced synthetic lethality combined with PARP1 inhibition to sensitize radiotherapy and CDDP treatment of Cervical cancer (2015-7820) PI's NAP Franken, LJA Stalpers, J Crezee - Clinical evaluation of the benefit of planning based steering to improve effectiveness of hyperthermia in cervical cancer patients (2017-10873) PI's HP Kok, J Crezee, LJA Stalpers - Optimization of pancreatic cancer treatment using chemotherapy and hyperthermia (2020-12985) PI's HP Kok, J Crezee, MF Bijlsma - Postoperative Re-irradiaTion with or without HYPErthermia (2022-14605) PI D van den Bongard, A Bakker, S Curto, M van Maaren, H Crezee -Project leader NWO-ZonMw grant on small animal hyperthermia device (40-00506-98-16015) -co-PI NWO grant “Development personalized MR-guided thermo-chemotherapy for breast cancer (2022) Other: - member Treatment planning and modelling in hyperthermia task group COMAC BME Concerted Action, 4th Medical and Health Research Programme of the European Commission 1990-1992 - Co-Promotor University of Amsterdam for Petra Kok (2007), Martijn de Greef ( 2012), Edmond Balidemaj (2016), Caspar van Leeuwen (2018), Gerben Schooneveldt (2019), Akke Bakker (2021), Roxan Helderman (2023), Daan Löke (2023); co-promotor Utrecht University for Soraya Gavazzi (2020), - Member PhD committee Judith Bergs (University of Amsterdam 2007), Hana Dobsicek-Trefna (Chalmers University, Göteborg 2010), Richard Canters (Erasmus University 2013), Marianne Linthorst (Erasmus University 2016), Tom Arends (Radboud University 2016), Mathias Weyland (Fribourg Switzerland 2020), Hans van Valenberg (Radboud University 2021) - Principal Investigator hyperthermia research AMC (2008-present). - Member Quality Assurance committee of the Interdisciplinary Working Group Hyperthermia (IAH), the German Cancer Society “Atzelsberg circle” (2010-present). - Secretary Maurits and Anna de Kock Foundation (2011-) - Board member, secretary, president European Society for Hyperthermic Oncology ESHO (2011-2014, 2018-, 2022-) - Member technical committee European Society for Hyperthermic Oncology ESHO (2011-present) - Host prof Rolf Issels (Munich), Spinoza chair at University of Amsterdam 8-10 Nov 2011 - Organisation of annual meetings Hyperthermia Working Group of the Dutch Cancer Society (2011, 2014). - Editorial Board/section editor International Journal of Hyperthermia (2013/2017-present)