Christine Helsen - KU Leuven | 人才画像

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Discovery of a Novel Androgen Receptor Antagonist, MEL-6, with Stereoselective Activity and Optimization of Its Metabolic Stability

Christine Helsen,Konstantina Karypidou,Joice Thomas,Wout De Leger,Tien Nguyen,Steven Joniau,Arnout Voet,Wim Dehaen,Frank Claessens

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2024)

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Structural Mechanism Underlying Variations in DNA Binding by the Androgen Receptor

Xiao Yin Lee, Wout Van Eynde,Christine Helsen, Hanne Willems, Kaat Peperstraete,Sofie De Block,Arnout Voet,Frank Claessens

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY（2024）

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Androgen Deprivation Modulates the Adrenocortical Stress Response

V Sommers,Max Gentenaar,Eva M. G. Viho,Christine Helsen,Vanessa Dubois,Jan Kroon,Brigitte Decallonne,Frank Claessens, Marcos Corrêa

Endocrine abstracts (2023)

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Supplementary Figure 5 from Identification and Characterization of MEL-3, a Novel AR Antagonist That Suppresses Prostate Cancer Cell Growth

Christine Helsen,Arnaud Marchand,Patrick Chaltin,Sebastian Munck,Arnout Voet,Annemieke Verstuyf,Frank Claessens

crossref（2023）

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Supplementary Figure Legend from Identification and Characterization of MEL-3, a Novel AR Antagonist That Suppresses Prostate Cancer Cell Growth

Christine Helsen,Arnaud Marchand,Patrick Chaltin, Sebastian Munck, Arnout Voet,Annemieke Verstuyf,Frank Claessens

crossref（2023）

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Study of Novel Androgen Receptor V770 Variant in Androgen Insensitivity Syndrome Patients Reveals the Transitional State of the Androgen Receptor Ligand Binding Domain Homodimer

Christine Helsen,Maria Santa Rocca,Tien T. Nguyen,Roy Eerlings,Xiao Yin Lee,Sofie De Block,Cinzia Vinanzi,Francesco Di Millo,Vito Giagulli,Arnout Voet,Alberto Ferlin,Frank Claessens

Protein science（2023）

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Supplementary Tables S1-S2 and Figures S1-S15 from the Effect of F877L and T878A Mutations on Androgen Receptor Response to Enzalutamide

Stefan Prekovic,Martin E. van Royen,Arnout R.D. Voet,Bart Geverts,Rene Houtman,Diana Melchers,Kam Y.J. Zhang, Thomas Van den Broeck,Elien Smeets,Lien Spans,Adriaan B. Houtsmuller,Steven Joniau,Frank Claessens,Christine Helsen

crossref（2023）

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Supplementary Figure from Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors

Christine Helsen,Tien T. Nguyen,Xiao Yin Lee,Roy Eerlings,Nikolaos Louros,Joost Schymkowitz,Frederic Rousseau,Frank Claessens,Arnout Voet

openalex（2023）

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