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个人简介
Her research focuseson immune regulation in solid organ transplantation, primarily lung, heart and liver transplantation.and with a special interest in ischemia/reperfusion injury. Coming from the cancer filed at theGerman Cancer Research Center in Heidelberg, she sees tumor and transplant immunology as twosides of the same coin - on one hand with the chance, to learn from solid tumors how they protectthemselves from immune recognition and rejection. On the other hand, with the chance to learnfrom transplanted organs what it takes to reject allografts. in both situations, there are commondenominators of rejection, i.e. specialized innate and adaptive immune cells andcytokine/chemokine networks, which orchestrate immune responses and may represent biomarkercandidates. The group has established an immunomics portfolio for immune monitoring of solidorgan transplant recipients comprising flow cytometry panels for immune cells, multiplex analysesfunctional assays and expression profiling. The complexity of the immune contexture intransplantation needs to be analyzed by advanced statistical methods like unsupervised clusterprincipal component analyses. All projects are performed in close collaboration with clinicalcolleagues at MHH and abroad - the most effective way to approach complex clinical questionswith sophisticated techniques.
研究兴趣
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#Papers: 554
#Citation: 10936
H-Index: 51
G-Index: 96
Sociability: 8
Diversity: 4
Activity: 155
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