Christian B. Macdonald - Program in Biophysics, University of Michigan

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论文共 30 篇作者统计合作学者相似作者

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Molecular Basis of Proton-Sensing by G Protein-Coupled Receptors

Matthew K Howard,Nicholas Hoppe,Xi-Ping Huang,Christian B Macdonald, Eshan Mehrota,Patrick Rockefeller Grimes, Adam Zahm,Donovan D Trinidad,Justin English,Willow Coyote-Maestas,Aashish Manglik

bioRxiv the preprint server for biology (2024)

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Deep Mutational Scanning of EccD3 Reveals the Molecular Basis of Its Essentiality in the Mycobacterium ESX Secretion System

Donovan D Trinidad,Christian B Macdonald,Oren S Rosenberg,James S Fraser,Willow Coyote-Maestas

bioRxiv the preprint server for biology (2024)

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Rosace: a Robust Deep Mutational Scanning Analysis Framework Employing Position and Mean-Variance Shrinkage

Jingyou Rao, Ruiqi Xin,Christian Macdonald, Matthew K. Howard,Gabriella O. Estevam,Sook Wah Yee, Mingsen Wang,James S. Fraser,Willow Coyote-Maestas,Harold Pimentel

GENOME BIOLOGY（2024）

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The Full Spectrum of SLC22 OCT1 Mutations Illuminates the Bridge Between Drug Transporter Biophysics and Pharmacogenomics

Sook Wah Yee,Christian B. Macdonald,Darko Mitrovic,Xujia Zhou,Megan L. Koleske, Jia Yang,Dina Buitrago Silva,Patrick Rockefeller Grimes,Donovan D. Trinidad,Swati S. More,Linda Kachuri,John S. Witte,Lucie Delemotte,Kathleen M. Giacomini,Willow Coyote-Maestas

MOLECULAR CELLno. 10 (2024)

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Mapping Kinase Domain Resistance Mechanisms for the MET Receptor Tyrosine Kinase Via Deep Mutational Scanning

Gabriella O Estevam,Edmond M Linossi,Jingyou Rao,Christian B Macdonald,Ashraya Ravikumar, Karson M Chrispens, John A Capra,Willow Coyote-Maestas,Harold Pimentel,Eric A Collisson,Natalia Jura,James S Fraser

crossref（2024）

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A Suite of Foundation Models Captures the Contextual Interplay Between Codons

Mohsen Naghipourfar, Siyu Chen, Mathew K Howard,Christian B Macdonald,Ali Saberi, Timo Hagen, Mohammad R K Mofrad,Willow Coyote-Maestas, Hani Goodarzi

bioRxiv the preprint server for biology (2024)

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Conserved Regulatory Motifs in the Juxtamembrane Domain and Kinase N-lobe Revealed Through Deep Mutational Scanning of the MET Receptor Tyrosine Kinase Domain

Gabriella O Estevam,Edmond M Linossi,Christian B Macdonald, Carla A Espinoza,Jennifer M Michaud,Willow Coyote-Maestas,Eric A Collisson,Natalia Jura,James S Fraser

bioRxiv the preprint server for biology (2024)

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Decision letter: Nitrogenase resurrection and the evolution of a singular enzymatic mechanism

Matilda Newton,Christian B Macdonald

crossref（2023）

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Studying Protein Variation in Evolution, Disease, and Biology Through Deep Insertion, Deletion, and Missense Mutational Scanning

Christian B. Macdonald

Biophysical journal（2023）

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DIMPLE: Deep Insertion, Deletion, and Missense Mutation Libraries for Exploring Protein Variation in Evolution, Disease, and Biology

Christian B. Macdonald,David Nedrud,Patrick Rockefeller Grimes,Donovan Trinidad,James S. Fraser,Willow Coyote-Maestas

GENOME BIOLOGYno. 1 (2023)

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