Chi-Lin Kuo - Department of Nuclear Medicine;Taipei Medical University Hospital;Department of Nuclear Medicine, Taipei Medical University Hospital

基本信息

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个人简介

I'm interested in the development of novel chemical tools to better understand lysosomal storage disorders. To achieve this purpose I study a set of chemically synthesized probes--the activity-based probes--that target and report distinct glycosidases whose deficiency underlie different lysosomal storage disorders.

研究兴趣

论文共 38 篇作者统计合作学者相似作者

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Corrigendum: Xylose-Configured Cyclophellitols As Selective Inhibitors for Glucocerebrosidase

Qin Su,Sybrin P Schröder,Lindsey T Lelieveld,Maria J Ferraz,Marri Verhoek,Rolf G Boot,Herman S Overkleeft,Johannes M F G Aerts,Marta Artola,Chi-Lin Kuo

ChemBioChemno. 3 (2023)

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The Development of a Broad-Spectrum Retaining Β-Exo-galactosidase Activity-Based Probe

Chi-Lin Kuo,Qin Su,Adrianus M. C. H. van den Nieuwendijk,Thomas J. M. Beenakker,Wendy A. Offen,Lianne I. Willems,Rolf. G. Boot,Alexi J. Sarris,Andre R. A. Marques,Jeroen D. C. Codee,Gijsbert A. van der Marel,Bogdan I. Florea,Gideon J. Davies,Herman S. Overkleeft,Johannes M. F. G. Aerts

Organic &amp Biomolecular Chemistry（2023）

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1,6-epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal a-Glucosidase Stabilizer for the Treatment of Pompe Disease

Ken Kok,Chi-Lin Kuo,Rebecca E. Katzy,Lindsey T. Lelieveld,Liang Wu,Veronique Roig-Zamboni,Gijsbert A. van der Marel,Jeroen D. C. Codee,Gerlind Sulzenbacher,Gideon J. Davies,Herman S. Overkleeft, Johannes M. F. G. Aerts,Marta Artola

Journal of the American Chemical Society（2022）

引用4浏览0WOS引用

Corrigendum: Xylose‐Configured Cyclophellitols As Selective Inhibitors for Glucocerebrosidase

Qin Su,Sybrin P. Schröder,Lindsey T. Lelieveld,Maria J. Ferraz,Marri Verhoek,Rolf G. Boot,Herman S. Overkleeft,Johannes M. F. G. Aerts,Marta Artola,Chi‐Lin Kuo

ChemBioChem (2022)

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Bs164 in complex with mannocyclophellitol aziridine

N. McGregor, T. Beenakker,C.L. Kuo, C.S. Wong, W.A. Offren,Z. Armstrong,J.D.C. Codee, J.M.F.G. Aerts,B.I. Florea,H. Overkleeft, G.J. Davies

crossref（2022）

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HEPES‐buffering of Bicarbonate‐containing Culture Medium Perturbs Lysosomal Glucocerebrosidase Activity

Martijn J. C. van der Lienden,Jan Aten,Rolf G. Boot,Marco van Eijk,Johannes M. F. G. Aerts,Chi-Lin Kuo

Journal of cellular biochemistry（2022）

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Synthesis of Broad-Specificity Activity-Based Probes for Exo-Β-mannosidases

Nicholas G. S. McGregor,Chi-Lin Kuo,Thomas J. M. Beenakker, Chun-Sing Wong,Wendy A. Offen,Zachary Armstrong,Bogdan Florea,Jeroen D. C. Codee,Herman S. Overkleeft,Johannes M. F. G. Aerts,Gideon J. Davies

Organic & biomolecular chemistry（2022）

引用3浏览0WOS引用

Activity-Based Protein Profiling of Retaining Α-Amylases in Complex Biological Samples

Yurong Chen,Zachary Armstrong,Marta Artola,Bogdan Florea,Chi-Lin Kuo,Casper de Boer, Mikkel S. Rasmussen,Maher Abou Hachem,Gijsbert A. van der Marel,Jeroen D. C. Codee, Johannes M. F. G. Aerts,Gideon J. Davies,Herman S. Overkleeft

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY（2021）

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Pre-clinical proof of concept of an AAV5-GLA gene therapy for Fabry disease resulting in crosscorrection in GLA-KO mice and non-human primates in target organs

J. M. P. Liefhebber, G. Brasser, I. Revers, L. Paerels, G. Squeri, L. K. Schwarz,L. Spronck, M. Oudshoorn-Dickmann,M. J. Ferraz,R. Ottenhoff,I. L. Pereira, L. Allart, S. Tripathi,C. Kuo, P. Montenegro-Miranda,C. J. M. de Vries, J. M. F. G. Aerts, Y. Poi-Liu

HUMAN GENE THERAPYno. 19-20 (2021): A8-A9

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Xylose-Configured Cyclophellitols As Selective Inhibitors for Glucocerebrosidase

Qin Su,Sybrin P. Schroder,Lindsey T. Lelieveld,Maria J. Ferraz,Marri Verhoek,Rolf G. Boot,Herman S. Overkleeft,Johannes M. F. G. Aerts,Marta Artola,Chi-Lin Kuo

CHEMBIOCHEMno. 21 (2021): 3090-3098

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