Charlotte Elder's main research area is adrenal insufficiency, with the development of a non-invasive Short Synacthen Test (diagnostic test), using a novel formulation of Synacthen (Nasacthin) for nasal administration and the measurement of the glucocorticoid response in saliva samples. She has led a team over five pharmacokinetic studies in adults and children and is currently working up the next phase of clinical trials. There is a patent application filed for the novel formulation and both commercial and research arms to the current workstream. She is the lead for a clinical trial looking to determine whether awakening salivary cortisone is an effective screening test for adrenal insufficiency in children (SCAIT-junior study) and is working on novel approaches to salivary collection in very young children and babies (NITS study). She is involved with other related projects, particularly involving iatrogenic adrenal insufficiency caused by prescription corticosteroids. Charlotte's other research interests include a cross-discipline bioengineering project developing pubertal simulation tools for training purposes.