Charles Birts - University of Southampton

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Bio

The aim of our work is to investigate immune cell function within the tumour microenvironment and determine how we can use antibody-glycan biology and metabolic intervention to fine tune antibody effector functions.

Research Interests

Papers共 24 篇Author StatisticsCo-AuthorSimilar Experts

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Could Anionic LDL Be a Ligand for RAGE and TREM2 in Addition to LOX-1 and Thus Exacerbate Lung Disease and Dementia

Charles N. Birts,David C. Wilton

Biochimica et biophysica acta Molecular basis of diseaseno. 8 (2023): 166837-166837

Cited0Views0WOSBibtex

The Role of Three-Dimensional in Vitro Models in Modelling the Inflammatory Microenvironment Associated with Obesity in Breast Cancer

Rhianna Blyth,Charles N. Birts,Stephen A. Beers

Breast cancer research（2023）

Cited0Views0Bibtex

Fcγ Receptor–mediated Cross-Linking Codefines the Immunostimulatory Activity of Anti-Human CD96 Antibodies

Anne Rogel, Fathima M. Ibrahim,Stephen M. Thirdborough,Florence Renart-Depontieu,Charles N. Birts,Sarah L. Buchan,Xavier Preville,Emma V. King,Aymen Al-Shamkhani

JCI insight（2022）

Cited2Views0WOSBibtex

Age, Obesity and Hyperglycaemia: Activation of Innate Immunity Initiates a Series of Molecular Interactions Involving Anionic Surfaces Leading to COVID-19 Morbidity and Mortality

Charles N. Birts,David C. Wilton

Medical Hypotheses（2021）

Cited6Views0WOSBibtex

Clinical Significance of Crown-Like Structures to Trastuzumab Response in Patients with Primary Invasive HER2+ Breast Cancer

Constantinos Savva,Charles N. Birts,Stephanie A. Laversin,Alicia Lefas,Jamie Krishnan,Aron Schapira,Margaret Ashton-Key,Max Crispin,Peter W. M. Johnson,Jeremy P. Blaydes,Ellen Copson,Ramsey I. Cutress,Stephen A. Beers

Journal of clinical oncology（2021）

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P53 is Regulated by Aerobic Glycolysis in Cancer Cells by the CtBP Family of NADH-dependent Transcriptional Regulators

Charles N. Birts,Arindam Banerjee,Matthew Darley,Charles R. Dunlop, Sarah Nelson, Sharandip K. Nijjar,Rachel Parker,Jonathan West,Ali Tavassoli,Matthew J. J. Rose-Zerilli,Jeremy P. Blaydes

Science signaling（2020）

Cited28Views0WOSSCIENCEBibtex

Glycolysis, Via NADH-dependent Dimerisation of CtBPs, Regulates Hypoxia-Induced Expression of CAIX and Stem-Like Breast Cancer Cell Survival

Mira Kreuzer,Arindam Banerjee,Charles N. Birts,Matthew Darley,Ali Tavassoli,Mircea Ivan,Jeremy P. Blaydes

FEBS letters（2020）

Cited4Views0WOSBibtex

Author Correction: Authentication and Characterisation of a New Oesophageal Adenocarcinoma Cell Line: MFD-1

Edwin Garcia,Annette Hayden,Charles N. Birts,Edward Britton,Connor Rogerson,Christopher W. Bleaney,Andrew Cowie,Karen Pickard,Massimiliano Mellone,C Choh,Mathieu Derouet,Patrick J. Duriez,Fergus Noble,Michael J. White,John Primrose, Jonathan C. Strefford,Matthew Rose‐Zerilli,Gareth J. Thomas,Yeng Ang,Andrew D Sharrocks,Rebecca C. Fitzgerald,Tim Underwood,Shona MacRae,Nicola Grehan,Zarah Abdullahi,Rachel de la Rue,Ayesha Noorani, Rachael Fels Elliott,Nadeera de Silva,Jan Bornschein,Maria O’Donovan,Gianmarco Contino,Tsun-Po Yang,Hamza Chettouh,Jason Crawte,Barbara Nutzinger,Paul A. Edwards,Laura Smith,Ahmad Miremadi,Shalini Malhotra, Alison D. Cluroe,Richard Hardwick, Jim Davies,Hugo Ford,David Gilligan,Peter Safranek,Andrew Hindmarsh,Vijayendran Sujendran, Nick Carroll,Richard Turkington,Stephen J. Hayes,Shaun R. Preston, Sarah Oakes,Izhar Bagwan,Vicki Save,Richard J. E. Skipworth,Ted R. Hupp,J. Robert O’Neill,Olga Tucker,Philippe Taniere, Jack Owsley,Charles Crichton, Christian Schusterreiter,Hugh Barr,Neil A. Shepherd,Oliver Old,Jesper Lagergren,James Gossage,Andrew Davies,Fuju Chang,Janine Zylstra,Grant Sanders,Richard Berrisford, Catherine Harden,David Bunting,Michael Lewis, Ed Cheong,Bhaskar Kumar,Simon L. Parsons,Irshad Soomro,Philip Kaye,John R. Saunders,Laurence Lovat, Rehan Haidry, Victor Eneh,Laszlo Igali,I. Welch, Michael Scott, Shamila Sothi, Sari Suortamo, Suzy Lishman,Duncan Beardsmore,Charlotte Anderson,Mike L. Smith,Maria Secrier,Matthew Eldridge,Lawrence Bower,Achilleas Achilleos,Andy G. Lynch,Simon Tavaré

Scientific reports（2019）

Cited1Views0Bibtex

Stem Cell-Like Breast Cancer Cells with Acquired Resistance to Metformin Are Sensitive to Inhibitors of NADH-dependent CtBP Dimerization

Arindam Banerjee,Charles N. Birts,Matthew Darley,Rachel Parker,Alex H. Mirnezami,Jonathan West,Ramsey Cutress,Stephen A. Beers,Matthew J. J. Rose-Zerilli,Jeremy P. Blaydes

Carcinogenesis（2019）

Cited28Views0WOSBibtex

Author Correction: Authentication and Characterisation of a New Oesophageal Adenocarcinoma Cell Line: MFD-1 (scientific Reports, (2016), 6, 1, (32417), 10.1038/Srep32417)

García,Annette Hayden,Charles N. Birts,Edward Britton,Connor Rogerson,Christopher W. Bleaney,Andrew Cowie, K. W. Pickard,Massimiliano Mellone, C Choh,Mathieu Derouet,Patrick J. Duriez,Fergus Noble,Michael J. White,John Primrose, Jonathan C. Strefford,Matthew Rose‐Zerilli,Gareth J. Thomas,Yeng Ang,Andrew D. Sharrocks, Rebecca C. Fitzgerald,Timothy J. Underwood,Shona MacRae, Nicola Grehan,Zarah Abdullahi,Rachel de la Rue,Ayesha Noorani, Rachael Fels Elliott,Nadeera de Silva,Jan Bornschein,Maria O’Donovan,Gianmarco Contino,Tsun-Po Yang,Hamza Chettouh,Jason Crawte,Barbara Nutzinger,Paul A. Edwards, Laura Smith,Ahmad Miremadi, Shalini Malhotra, Alison D. Cluroe,Richard Hardwick, Jim Davies,Hugo Ford, David Gilligan,Peter Safranek,Stephen J. Hayes, Andrew Davies,John R. Saunders, Michael Scott

openalex（2019）

Cited0Views0Bibtex

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