His research interest are in diagnostic testing in the emergency department setting, particularly imaging tests such as ultrasound and computed tomography. He has been funded by the Agency for Healthcare Research and Quality (AHRQ) on R-level grants to minimize CT overutilization and is currently funded by the Biomedical Advanced Research Development Authority (BARDA) to help develop automated intelligence (AI) solutions for lung ultrasound in COVID-19.

In addition to his research, Dr. Moore oversees education in point-of-care ultrasound including the teaching of medical students, residents, fellows, and directing national CME conferences. He has lectured internationally in Europe, China, South America, and New Zealand. On a clinical level Dr. Moore has worked within Yale New Haven Hospital to establish clinical ultrasound privileges and has overseen the training of attending physicians in the Department of Emergency Medicine. He is chair of the Yale Point-of-care Ultrasound Council (YPUC), a multidisciplinary group devoted to enhancing quality of point-of-care ultrasound within YNHH.