Douglas Green (born 1955), is an American biologist. He holds the Peter C. Doherty Endowed Chair of Immunology in St. Jude Children's Research Hospital. Green received his PhD from Yale.

His research has focused on the process of active cell death and cell survival, extending from the role of cell death in cancer regulation and immune responses in the whole organism to the fundamental molecular events directing the death of the cell. Green is editor in chief of the Nature Publishing Group journal Oncogene (journal). He is the author of the book Cell Death, Means To An End.