Date of birth: March 4, 1966 Place of birth: Empoli (Florence) Dr Betti Giusti scientific activity has been dedicated to the comprehension of pathophysiologic mechanisms and molecular bases of atherosclerotic and thromboembolic diseases, and extracellular matrix disorders. Since her graduation she has been devoted to research on lympho-monocyte relationships, events associated to lymphocyte-induced monocyte activation, such as cytokine production and procoagulant activity, and role of different lymphocyte subpopulations during immune responses. Her current research interests include pathophysiology of thrombophilic states and clinical significance of hypercoagulability markers and, in particular, the role of inflammation and immune response in cardiovascular diseases. Part of her present activity is in the field of personalized medicine, and, in particular, in defining the molecular mechanisms of individual response to antiaggregant, anticoagulant, lipid lowering and antihypertensive therapies. In particular, as concerns the molecular mechanisms of residual platelet reactivity on antiaggregant therapy in high risk vascular patients she widely investigated the pharmacogenetics contribution. Moreover, her interest has been dedicated to the evaluation of molecular bases of multifactorial diseases in the field of cardiovascular disease by studying mutations/polymorphisms in candidate susceptibility genes. A further issue of research is represented by the study of the molecular bases of extracellular matrix diseases, such as Marfan syndrome, abdominal and thoracic aortic aneurysms, Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Dr Betti Giusti scientific activity was documented by the presence as co-authors of 200 papers on peer reviewed journals (H-Index=45 scopus, 52 Google Scholar). In the fields of scientific interests, Dr Giusti has been involved in the set-up, standardization of diagnostic test and automation of several molecular biology approaches: identification of polymorphisms associated to arterial and venous thromboembolism (Factor V Leiden, FIIG20210A, C677T MTHFR, etc.); molecular characterization of mutations in fibrillin 1 gene in Marfan syndrome and related diseases patients; molecular characterization of mutations in COL6A1, COL6A2 and COL6A3 genes in Bethlem myopathy, Ullrich scleroatonic muscular dystrophy and related disorders patients. In the last years, Dr Betti Giusti has dedicated her efforts in set-up, optimization and application in the fields of scientific interests of microarray technology both for gene expression profiling (Affymetrix technology and two colour technology) and mutation/polymorphism genotyping (GenomeLab SNPStream technology, electronic microchip technology, Nanosphere technology). Moreover, she is involved in the utilization for research and diagnostic purposes of the high-throughput sequencing technology (Roche). Didactics Activity - Technologies in Biotechnology and Biotechnology Laboratory, Degree in Biotechnology, University of Florence; - Diagnostics in Vascular Disease, M.Sc. in Biotechnology, University of Florence; - Molecular Biology, M.Sc. in Sciences of Medical Diagnostics Technologies, University of Florence She is: member of the faculty of the PhD in Molecular Medicine (University of Siena) member of the faculty of the PhD in Non-linear Dynamics and Complex Systems (University of Florence) board member of the School of Specialization in Infectious Diseases (University of Florence) board member of the School of Specialization in Vascular Surgery (University of Florence) Dr Giusti has lectured at numerous university courses, training courses or conferences as expert or invited speaker In the field of interest Dr Giusti was tutor of numerous degree theses: Degree in Medicine and Surgery, Degree in Biology, Degree in Sciences of Medical Diagnostics Technologies, Degree in Biotechnology.