基本信息
浏览量:226
职业迁徙
个人简介
Research Interests
My laboratory is interested in innovative anticancer agents, targeted cancer therapy, the mechanisms of action of and/or resistance to anticancer agents, and molecular signatures or biomarkers for predicting treatment response or early diagnosis of lung cancers. Current study includes TRAIL-armed oncolyticadenovirotherapy, small molecules targeted to K-Ras and the C-terminal domain of RNA polymerase II, biomarkers in primary lung cancer, and molecular signatures of response to targeted therapy in lung cancer. Our long term goal is to develop pathway-targeted therapeutic agents that are minimally toxic and highly effective to treat refractory tumors and identify molecular signatures for predicting response or early diagnosis.
My laboratory is interested in innovative anticancer agents, targeted cancer therapy, the mechanisms of action of and/or resistance to anticancer agents, and molecular signatures or biomarkers for predicting treatment response or early diagnosis of lung cancers. Current study includes TRAIL-armed oncolyticadenovirotherapy, small molecules targeted to K-Ras and the C-terminal domain of RNA polymerase II, biomarkers in primary lung cancer, and molecular signatures of response to targeted therapy in lung cancer. Our long term goal is to develop pathway-targeted therapeutic agents that are minimally toxic and highly effective to treat refractory tumors and identify molecular signatures for predicting response or early diagnosis.
研究兴趣
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作者统计
#Papers: 473
#Citation: 16412
H-Index: 62
G-Index: 115
Sociability: 9
Diversity: 0
Activity: 5
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