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Genomic studies have identified new mechanisms that underlie the development of cancer and revealed targets for novel therapies. Together with transcriptomic and epigenetic analyses, cancer entities are nowadays classified by their molecular features. In addition to the mutated cancer cells, other cellular compartments of solid tumors, including cancer associated fibroblasts and immune cells influence the clinical behavior of cancer patients.
Our lab uses next generation sequencing approaches to characterize cancer on the genomic, transcriptomic and epigenetic level. Using integrative analyses, we try to find molecular patterns that correlate with and potentially explain the different clinical categories of patients. By applying single cell sequencing approaches, we aim at identifying pathways that are altered in the different compartments of the tumor, including the stroma, that provide potential new targets for intervention.
Our lab uses next generation sequencing approaches to characterize cancer on the genomic, transcriptomic and epigenetic level. Using integrative analyses, we try to find molecular patterns that correlate with and potentially explain the different clinical categories of patients. By applying single cell sequencing approaches, we aim at identifying pathways that are altered in the different compartments of the tumor, including the stroma, that provide potential new targets for intervention.
Research Interests
Papers共 193 篇Author StatisticsCo-AuthorSimilar Experts
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Patrick S. Plum,Timo Hess,Denis Bertrand, Isabelle Morgenstern,Oscar Velazquez Camacho, Christoph Jonas,Christina Alidousty, Britta Wagner,Stephanie Roessler,Thomas Albrecht,Jessica Becker, Vanessa Richartz,Barbara Holz,Sascha Hoppe,Huay Mei Poh,Burton Kuan Hui Chia,Cheryl Xueli Chan,Thushangi Pathiraja,Audrey S. M. Teo,Jens U. Marquardt,Alexis Khng,Michael Heise,Yao Fei,Rene Thieme,Sebastian Klein,Jing Han Hong,Simona O. Dima,Irinel Popescu,Maria Hoppe-Lotichius,Reinhard Buettner,Anja Lautem,Gerd Otto,Alexander Quaas,Niranjan Nagarajan,Steve Rozen,Bin Tean Teh,Benjamin Goeppert,Uta Drebber,Hauke Lang,Patrick Tan,Ines Gockel,Johannes Schumacher,Axel M. Hillmer
Clinical and Translational Medicineno. 6 (2024)
Cell systemsno. 11 (2024): 1061-1074.e7
Maria Alejandra Garcia-Marquez,Martin Thelen,Eugen Bauer,Lukas Maas,Kerstin Wennhold,Jonas Lehmann,Diandra Keller,Milos Nikolic,Julie George,Thomas Zander,Wolfgang Schroeder, Philipp Mueller,Ali M. Yazbeck,Christiane Bruns,Roman Thomas,Birgit Gathof,Alexander Quaas,Martin Peifer,Axel M. Hillmer,Michael von Bergwelt-Baildon,Hans Anton Schloesser
JOURNAL FOR IMMUNOTHERAPY OF CANCERno. 4 (2024)
Luise Nagel, Marten Wenzel, Sascha Hoppe, Patrick S. Plum, Mohammad Karimpour, Marek Franitza,Roger Wahba, Marc Bludau,Christiane J Bruns,Alexander Quaas,Andreas Beyer,Axel Hillmer
biorxiv(2024)
Christoph Arolt,Andreas H Scheel, Margaret Dugan, Robert Wild, Vanessa Richartz,Barbara Holz,Johannes Brägelmann,Svenja Wagener-Ryczek,Sabine Merkelbach-Bruse,Juergen Wolf,Reinhard Buettner, Luigi Catanzariti,Matthias Scheffler,Axel M Hillmer
NPJ precision oncologyno. 1 (2024): 259-259
Joerg Kumbrink,Melanie-Christin Demes,Jan Jeroch,Andreas Braeuninger, Kristin Hartung, Uwe Gerstenmaier,Ralf Marienfeld,Axel Hillmer, Nadine Bohn, Christina Lehning, Ferdinand Ferch,Peter Wild,Stefan Gattenloehner,Peter Moeller,Frederick Klauschen, Andreas Jung
PATHOLOGY & ONCOLOGY RESEARCH (2024)
H. A. Schlößer,A. Lohneis, M. A. Garcia-Marquez,P. Schiller, K. Rosenberger, M. Thelen,K. Wennhold, E. Bauer,B. Gathof, N. Wirsik, L. Lukomski, M. Hallek, R. Büttner,A. Hillmer, M. Hellmich, W. Schröder,M. von Bergwelt-Baildon,A. Quaas,C. Bruns, T. Zander
Xiaodong Liu,Ke Zhang,Neslihan A. Kaya,Zhe Jia,Dafei Wu, Tingting Chen, Zhiyuan Liu,Sinan Zhu,Axel M. Hillmer,Torsten Wuestefeld,Jin Liu,Yun Shen Chan,Zheng Hu,Liang Ma,Li Jiang,Weiwei Zhai
Nature Communicationsno. 1 (2024)
A. Stickelmann,H. Scharpenseel,J. Siemanowski,F. Malchers,I Terjung,A. Hillmer,S. Meemboor, S. Mrkelbach-Bruse,A. H. Scheel,C. Woempner,M. Scheffler,R. Riedel,S. Michels,A. Eisert,R. N. Fischer, L. Ruge, F. John,E. Passmann, M. Brodersen,T. G. Blum,S. Stephan-Falkenau,N. Kosse,F. Saalfeld, G. Tritchkova,C. Schubart,L. Toegel, Noelle F. Thielert,M. Wiesweg,A. Braeuninger,B. Eul,F. C. Althoff,M. Demes,A. Stenzinger,P. Christopoulos,U. Graeven, E. Berezucki,N. P. Konstandin,S. Stilgenbauer,F. Ruecker,J. Kulhavy,H. -D Hummel,R. Buettner,J. Wolf,L. Nogova
ONCOLOGY RESEARCH AND TREATMENT (2023): 146-147
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Author Statistics
#Papers: 193
#Citation: 9207
H-Index: 45
G-Index: 95
Sociability: 8
Diversity: 3
Activity: 78
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