Antony Oliver - University of Sussex

基本信息

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职业迁徙

个人简介

Our laboratory is focussed on the many dynamic protein-protein / protein-nucleic acid complexes involved in the intertwined processes of DNA repair and cell cycle control / checkpoints. We principally use the technique of X-ray crystallography to determine structures, but increasingly use NMR, SAXS and EM in hybrid-type methods.

研究兴趣

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Binding of the TRF2 Iddr Motif to RAD50 Highlights a Convergent Evolutionary Strategy to Inactivate MRN at Telomeres

Freddy Khayat,Majedh Alshmery,Mohinder Pal,Antony W. Oliver,Alessandro Bianchi

NUCLEIC ACIDS RESEARCHno. 13 (2024): 7704-7719

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Design and Synthesis of Quinazolin-4-one Derivatives As Potential Anticancer Agents and Investigation of Their Interaction with RecQ Helicases

Hanan S. Haggag,Shaimaa M. Aboukhatwa,Mohamed S. Nafie, Anju Paul,Nabaweya Sharafeldin,Antony W. Oliver,Mervat H. El-Hamamsy

BIOORGANIC CHEMISTRY (2024)

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CC-seq: Nucleotide-Resolution Mapping of Spo11 DNA Double-Strand Breaks in S. cerevisiae Cells

George G B Brown,Will H Gittens,Rachal M Allison,Antony W Oliver,Matthew J Neale

Methods in molecular biology (Clifton, N.J.) (2024): 3-22

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The Mitotic CIP2A-TOPBP1 Axis Facilitates Mitotic Pathway Choice Between MiDAS and MMEJ

Peter Ryan Martin,Jadwiga Nieminuszczy, Zuza Kozik, Nihal Jakub, Maxime Lecot,Julia Vorhauser, Karen A Lane, Alexandra Kanellou,Jorg Mansfeld, Laurence H Pearl,Antony Oliver, Jessica A Downs, Jyoti Chaudhary, Matthew Day, Wojciech Niedzwiedz

biorxiv（2024）

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TopBP1 Utilises a Bipartite GINS Binding Mode to Support Genome Replication