Markowitz carries out nuclear and particle physics experiments at the Thomas Jefferson National Accelerator Facility, in Virginia and the European Center for Nuclear and Particle Physics (CERN) in Geneva, Switzerland. His research interests focus on the source of gravity, extra dimensions, black holes, quark structure of nuclei, dark matter, dark energy and the electro production of quarks and anti-quarks (or matter and anti-matter). Markowitz conducted a series of experiments measuring strange quark effects in atomic nuclei are mapping out the behavior of these elusive and unstable particles. The experiments use high energy accelerators to bombard various target materials and then to measure the subsequent particles which are produced.

During his time at FIU, Markowitz has taught Nuclear Physics, Intermediate Classical Mechanics, Modern Physic, Intermediate Laboratory, and the introductory physics sequences, as well as a FIG and the Freshman Experience course.