Angela Tramonti

Structure-function analyses of enzymes involved in vitamin B6 biosynthesis and salvage pathways. Studies on the molecular basis of neonatal epileptic encephalopathy. Structure-function relationships and regulation of gene expression of pyridoxal-5’-phosphate-dependent transcriptional regulators in bacteria. Biochemical studies on serine hydroxymethyltransferase and its role in cancer metabolic reprogramming. Identification and characterization of potential inhibitors.